Difference between revisions of "Spo0E"

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= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
 
{{SubtiWiki regulon|[[SigB regulon]]}},
 
{{SubtiWiki regulon|[[SigB regulon]]}},
{{SubtiWiki regulon|[[AbrB regulon]]}}
+
{{SubtiWiki regulon|[[AbrB regulon]]}},
 +
{{SubtiWiki regulon|[[Rok regulon]]}}
  
 
=The gene=
 
=The gene=
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* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 
** [[AbrB]]:  transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/2504584 PubMed]
 
** [[AbrB]]:  transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/2504584 PubMed]
 +
** [[Rok]]: transcription repression of the [[SigB]]-dependent promoter {{PubMed|22524514}}
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
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<pubmed>19995980 </pubmed>
 
<pubmed>19995980 </pubmed>
 
==Original Publications==
 
==Original Publications==
'''Additional publications:''' {{PubMed|22210769}}  
+
'''Additional publications:''' {{PubMed|22524514,22210769}}  
 
<pubmed>1901567,2838724,12180929,12067336,10747015,2118512,19332814,8127878,2504584, 12270811 11112444 </pubmed>
 
<pubmed>1901567,2838724,12180929,12067336,10747015,2118512,19332814,8127878,2504584, 12270811 11112444 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 15:59, 27 April 2012

Gene name spo0E
Synonyms
Essential no
Product Spo0A-P phosphatase
Function initiation of sporulation
Interactions involving this protein in SubtInteract: Spo0E
Function and regulation of this protein in SubtiPathways:
Phosphorelay
MW, pI 9 kDa, 6.483
Gene length, protein length 255 bp, 85 aa
Immediate neighbours ykvA, eag
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Spo0E context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Spo0E expression.png




























Categories containing this gene/protein

protein modification, phosphorelay

This gene is a member of the following regulons

SigB regulon, AbrB regulon, Rok regulon

The gene

Basic information

  • Locus tag: BSU13640

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: spo0E family (according to Swiss-Prot)
  • Paralogous protein(s): YnzD

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • Spo0E is degraded by FtsH
    • stress-induced expression of Spo0E by SigB results in prevention of sporulation during stress (due to dephosphorylation of Spo0A) PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Tony Wilkinson, York University, U.K. homepage

Your additional remarks

References

Reviews

Original Publications

Additional publications: PubMed