YmfD

• Description: exporter for the siderophore bacillibactin
  
  

Gene name	ymfD
Synonyms
Essential	no
Product	bacillibactin exporter
Function	iron acquisition
MW, pI	44 kDa, 8.355
Gene length, protein length	1206 bp, 402 aa
Immediate neighbours	ymfC, ymfF
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

transporters/ other, acquisition of iron, iron metabolism, membrane proteins

This gene is a member of the following regulons

Mta regulon

The gene

Basic information

• Locus tag: BSU16825

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: major facilitator superfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• Swiss prot entry: O31762

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: ymfD-ymfF-ymfH PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:
  • Mta: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Marcus Miethke, Sarah Schmidt, Mohamed A Marahiel
The major facilitator superfamily-type transporter YmfE and the multidrug-efflux activator Mta mediate bacillibactin secretion in Bacillus subtilis.
J Bacteriol: 2008, 190(15);5143-52
[PubMed:18502870] [WorldCat.org] [DOI] (I p)