Difference between revisions of "Spo0E"
| Line 40: | Line 40: | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| + | {{SubtiWiki regulon|[[SigB regulon]]}}, | ||
{{SubtiWiki regulon|[[AbrB regulon]]}} | {{SubtiWiki regulon|[[AbrB regulon]]}} | ||
| Line 83: | Line 84: | ||
* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
** [[Spo0F]]-[[Spo0E]] {{PubMed|12067336}} | ** [[Spo0F]]-[[Spo0E]] {{PubMed|12067336}} | ||
| − | ** | + | ** [[Spo0A]]-[[Spo0E]] {{PubMed|12067336}} |
* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
| Line 103: | Line 104: | ||
* '''Operon:''' ''spo0E'' {{PubMed|2838724}} | * '''Operon:''' ''spo0E'' {{PubMed|2838724}} | ||
| − | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|1901567}} | + | * '''[[Sigma factor]]:''' |
| + | ** [[SigA]] {{PubMed|1901567}}, [[SigB]] {{PubMed|22210769}} | ||
* '''Regulation:''' | * '''Regulation:''' | ||
** repressed during logrithmic growth ([[AbrB]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/2504584 PubMed] | ** repressed during logrithmic growth ([[AbrB]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/2504584 PubMed] | ||
| + | ** induced under stress conditions ([[SigB]]) {{PubMed|22210769}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
** [[AbrB]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/2504584 PubMed] | ** [[AbrB]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/2504584 PubMed] | ||
| − | * '''Additional information:''' Spo0E is degraded by [[FtsH]] | + | * '''Additional information:''' |
| + | ** Spo0E is degraded by [[FtsH]] | ||
| + | ** stress-induced expression of Spo0E by [[SigB]] results in prevention of sporulation during stress (due to dephosphorylation of [[Spo0A]]) {{PubMed|22210769}} | ||
=Biological materials = | =Biological materials = | ||
| Line 137: | Line 142: | ||
<pubmed>19995980 </pubmed> | <pubmed>19995980 </pubmed> | ||
==Original Publications== | ==Original Publications== | ||
| + | '''Additional publications:''' {{PubMed|22210769}} | ||
<pubmed>1901567,2838724,12180929,12067336,10747015,2118512,19332814,8127878,2504584, 12270811 11112444 </pubmed> | <pubmed>1901567,2838724,12180929,12067336,10747015,2118512,19332814,8127878,2504584, 12270811 11112444 </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 08:48, 4 January 2012
- Description: Spo0A-P phosphatase, control of the phosphorelay
| Gene name | spo0E |
| Synonyms | |
| Essential | no |
| Product | Spo0A-P phosphatase |
| Function | initiation of sporulation |
| Interactions involving this protein in SubtInteract: Spo0E | |
| Function and regulation of this protein in SubtiPathways: Phosphorelay | |
| MW, pI | 9 kDa, 6.483 |
| Gene length, protein length | 255 bp, 85 aa |
| Immediate neighbours | ykvA, eag |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
protein modification, phosphorelay
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU13640
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: spo0E family (according to Swiss-Prot)
- Paralogous protein(s): YnzD
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P05043
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: spo0E PubMed
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Tony Wilkinson, York University, U.K. homepage
Your additional remarks
References
Reviews
Original Publications
Additional publications: PubMed
