Difference between revisions of "TsaD"
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| − | * '''Description:''' O-sialoglycoprotein endopeptidase ( | + | * '''Description:''' there are two annotations for the corresponding ''E. coli'' protein: O-sialoglycoprotein endopeptidase, and required for threonyl carbamoyl adenosine (t6A) modification of tRNAs that pair with ANN codons in mRNA, [[universally conserved protein]] <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Product''' || O-sialoglycoprotein endopeptidase (putative) | |style="background:#ABCDEF;" align="center"| '''Product''' || O-sialoglycoprotein endopeptidase (putative) | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || tRNA modification |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/Gcp Gcp] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/Gcp Gcp] | ||
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[translation]]}}, | ||
{{SubtiWiki category|[[essential genes]]}}, | {{SubtiWiki category|[[essential genes]]}}, | ||
{{SubtiWiki category|[[universally conserved proteins]]}}, | {{SubtiWiki category|[[universally conserved proteins]]}}, | ||
| Line 66: | Line 67: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' |
| + | ** biosynthesis of the threonylcarbamoyladenosine (t6A) residue at position 37 of ANN-decoding tRNAs {{PubMed|21183954}} | ||
| + | ** conserved glycopeptidase that may be directly involved in the metabolism of glycated proteins {{PubMed|20824107}} | ||
* '''Protein family:''' peptidase M22 family (according to Swiss-Prot) | * '''Protein family:''' peptidase M22 family (according to Swiss-Prot) | ||
| Line 84: | Line 87: | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' the corresponding ''E. coli'' protein interacts with the proteins corresponding to [[YdiB]] and [[YdiC]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19376873 PubMed] | + | * '''[[SubtInteract|Interactions]]:''' |
| + | ** the corresponding ''E. coli'' protein interacts with the proteins corresponding to [[YdiB]] and [[YdiC]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19376873 PubMed] | ||
| − | * '''Localization:''' | + | * '''[[Localization]]:''' |
=== Database entries === | === Database entries === | ||
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=References= | =References= | ||
| − | + | ==Publications on the corresponding'' E. coli'' protein, YgjD== | |
| + | <pubmed> 21183954 19376873 20824107 21619589 </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 12:53, 1 August 2011
- Description: there are two annotations for the corresponding E. coli protein: O-sialoglycoprotein endopeptidase, and required for threonyl carbamoyl adenosine (t6A) modification of tRNAs that pair with ANN codons in mRNA, universally conserved protein
| Gene name | gcp |
| Synonyms | ydiE |
| Essential | yes PubMed |
| Product | O-sialoglycoprotein endopeptidase (putative) |
| Function | tRNA modification |
| Interactions involving this protein in SubtInteract: Gcp | |
| MW, pI | 36 kDa, 5.016 |
| Gene length, protein length | 1038 bp, 346 aa |
| Immediate neighbours | ydiD, ydiF |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
translation, essential genes, universally conserved proteins, poorly characterized/ putative enzymes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU05940
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: peptidase M22 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O05518
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Publications on the corresponding E. coli protein, YgjD
