Difference between revisions of "GerKA"
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=== Additional information=== | === Additional information=== | ||
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=The protein= | =The protein= | ||
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' | + | * '''[[SubtInteract|Interactions]]:''' |
| + | ** [[GerKA]]-[[GerKB]]-[[GerKC]] (tentative receptor complex) {{PubMed|21696470}} | ||
| + | ** [[GerKA]] is part of the [[germinosome]] in the spore inner membrane {{PubMed|21696470}} | ||
| − | * '''Localization:''' | + | * '''Localization:''' |
| + | ** spore inner membrane {{PubMed|21696470}} | ||
=== Database entries === | === Database entries === | ||
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=References= | =References= | ||
| − | <pubmed>16707705,16740944,,16352818, </pubmed> | + | <pubmed>16707705,16740944,21696470,16352818, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 12:18, 28 June 2011
- Description: nutrient receptor
| Gene name | gerKA |
| Synonyms | |
| Essential | no |
| Product | nutrient receptor |
| Function | germination response to the combination of glucose, fructose, aspartate, and KCl |
| MW, pI | 60 kDa, 5.206 |
| Gene length, protein length | 1632 bp, 544 aa |
| Immediate neighbours | yczF, gerKC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
germination, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU03700
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: gerABKA family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- spore inner membrane PubMed
Database entries
- Structure:
- UniProt: P49939
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor: SigG PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Keren K Griffiths, Jingqiao Zhang, Ann E Cowan, Ji Yu, Peter Setlow
Germination proteins in the inner membrane of dormant Bacillus subtilis spores colocalize in a discrete cluster.
Mol Microbiol: 2011, 81(4);1061-77
[PubMed:21696470]
[WorldCat.org]
[DOI]
(I p)
Krzysztof Hinc, Krzysztofa Nagórska, Adam Iwanicki, Grzegorz Wegrzyn, Simone J Séror, Michal Obuchowski
Expression of genes coding for GerA and GerK spore germination receptors is dependent on the protein phosphatase PrpE.
J Bacteriol: 2006, 188(12);4373-83
[PubMed:16740944]
[WorldCat.org]
[DOI]
(P p)
Takao Igarashi, Peter Setlow
Transcription of the Bacillus subtilis gerK operon, which encodes a spore germinant receptor, and comparison with that of operons encoding other germinant receptors.
J Bacteriol: 2006, 188(11);4131-6
[PubMed:16707705]
[WorldCat.org]
[DOI]
(P p)
Swaroopa Atluri, Katerina Ragkousi, Donna E Cortezzo, Peter Setlow
Cooperativity between different nutrient receptors in germination of spores of Bacillus subtilis and reduction of this cooperativity by alterations in the GerB receptor.
J Bacteriol: 2006, 188(1);28-36
[PubMed:16352818]
[WorldCat.org]
[DOI]
(P p)
