Difference between revisions of "GerAC"
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=== Additional information=== | === Additional information=== | ||
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
− | * '''Interactions:''' | + | * '''[[SubtInteract|Interactions]]:''' |
** [[GerAA]]-[[GerAB]]-[[GerAC]] (tentative receptor complex) {{PubMed|21378181,21378197}} | ** [[GerAA]]-[[GerAB]]-[[GerAC]] (tentative receptor complex) {{PubMed|21378181,21378197}} | ||
+ | ** [[GerAC]] is part of the [[germinosome]] in the spore inner membrane {{PubMed|21696470}} | ||
+ | |||
* '''Localization:''' cell membrane (according to Swiss-Prot) | * '''Localization:''' cell membrane (according to Swiss-Prot) | ||
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=References= | =References= | ||
'''Additional publications:''' {{PubMed|16740944}} | '''Additional publications:''' {{PubMed|16740944}} | ||
− | <pubmed>3110007,17573930,12670969,2110996,15774895,16497325,16352818, 8755877 21378181,21378197</pubmed> | + | <pubmed>3110007,17573930,12670969,2110996,15774895,16497325,16352818, 8755877 21378181,21378197 21696470</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 12:04, 28 June 2011
- Description: nutrient receptor, germination response to L-alanine
Gene name | gerAC |
Synonyms | |
Essential | no |
Product | nutrient receptor |
Function | germination response to L-alanine |
MW, pI | 42 kDa, 7.302 |
Gene length, protein length | 1119 bp, 373 aa |
Immediate neighbours | gerAB, liaR |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
Categories containing this gene/protein
germination, membrane proteins
This gene is a member of the following regulons
SigF regulon, SigG regulon, SpoVT regulon
The gene
Basic information
- Locus tag: BSU33070
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: gerABKC lipoprotein family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
- predicted to be in the spore inner membrane PubMed
Database entries
- Structure:
- UniProt: P07870
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
Keren K Griffiths, Jingqiao Zhang, Ann E Cowan, Ji Yu, Peter Setlow
Germination proteins in the inner membrane of dormant Bacillus subtilis spores colocalize in a discrete cluster.
Mol Microbiol: 2011, 81(4);1061-77
[PubMed:21696470]
[WorldCat.org]
[DOI]
(I p)
Wiyada Mongkolthanaruk, Gareth R Cooper, Julia S P Mawer, Raymond N Allan, Anne Moir
Effect of amino acid substitutions in the GerAA protein on the function of the alanine-responsive germinant receptor of Bacillus subtilis spores.
J Bacteriol: 2011, 193(9);2268-75
[PubMed:21378197]
[WorldCat.org]
[DOI]
(I p)
Gareth R Cooper, Anne Moir
Amino acid residues in the GerAB protein important in the function and assembly of the alanine spore germination receptor of Bacillus subtilis 168.
J Bacteriol: 2011, 193(9);2261-7
[PubMed:21378181]
[WorldCat.org]
[DOI]
(I p)
Venkata Ramana Vepachedu, Peter Setlow
Analysis of interactions between nutrient germinant receptors and SpoVA proteins of Bacillus subtilis spores.
FEMS Microbiol Lett: 2007, 274(1);42-7
[PubMed:17573930]
[WorldCat.org]
[DOI]
(P p)
Stephanie T Wang, Barbara Setlow, Erin M Conlon, Jessica L Lyon, Daisuke Imamura, Tsutomu Sato, Peter Setlow, Richard Losick, Patrick Eichenberger
The forespore line of gene expression in Bacillus subtilis.
J Mol Biol: 2006, 358(1);16-37
[PubMed:16497325]
[WorldCat.org]
[DOI]
(P p)
Swaroopa Atluri, Katerina Ragkousi, Donna E Cortezzo, Peter Setlow
Cooperativity between different nutrient receptors in germination of spores of Bacillus subtilis and reduction of this cooperativity by alterations in the GerB receptor.
J Bacteriol: 2006, 188(1);28-36
[PubMed:16352818]
[WorldCat.org]
[DOI]
(P p)
Takao Igarashi, Peter Setlow
Interaction between individual protein components of the GerA and GerB nutrient receptors that trigger germination of Bacillus subtilis spores.
J Bacteriol: 2005, 187(7);2513-8
[PubMed:15774895]
[WorldCat.org]
[DOI]
(P p)
Rosa-Martha Cabrera-Martinez, Federico Tovar-Rojo, Venkata Ramana Vepachedu, Peter Setlow
Effects of overexpression of nutrient receptors on germination of spores of Bacillus subtilis.
J Bacteriol: 2003, 185(8);2457-64
[PubMed:12670969]
[WorldCat.org]
[DOI]
(P p)
I Bagyan, J Hobot, S Cutting
A compartmentalized regulator of developmental gene expression in Bacillus subtilis.
J Bacteriol: 1996, 178(15);4500-7
[PubMed:8755877]
[WorldCat.org]
[DOI]
(P p)
I M Feavers, J Foulkes, B Setlow, D Sun, W Nicholson, P Setlow, A Moir
The regulation of transcription of the gerA spore germination operon of Bacillus subtilis.
Mol Microbiol: 1990, 4(2);275-82
[PubMed:2110996]
[WorldCat.org]
[DOI]
(P p)
A R Zuberi, A Moir, I M Feavers
The nucleotide sequence and gene organization of the gerA spore germination operon of Bacillus subtilis 168.
Gene: 1987, 51(1);1-11
[PubMed:3110007]
[WorldCat.org]
[DOI]
(P p)