Difference between revisions of "NhaC"
| Line 81: | Line 81: | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' | + | * '''[[SubtInteract|Interactions]]:''' |
| − | * '''Localization:''' cell membrane (according to Swiss-Prot) | + | * '''[[Localization]]:''' cell membrane (according to Swiss-Prot) |
=== Database entries === | === Database entries === | ||
| Line 99: | Line 99: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[nhaC]]'' {{PubMed|21815947}} |
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
| Line 109: | Line 109: | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| + | ** the mRNA is substantially stabilized upon depletion of [[Rny|RNase Y]] {{PubMed|21815947}} | ||
=Biological materials = | =Biological materials = | ||
| Line 129: | Line 130: | ||
=References= | =References= | ||
| − | + | <big>''Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J'' </big> | |
| + | <big>'''RNA processing in ''Bacillus subtilis'': identification of targets of the essential RNase Y.''' </big> | ||
| + | <big>Mol Microbiol. 2011 81(6): 1459-1473. </big> | ||
| + | [http://www.ncbi.nlm.nih.gov/pubmed/21815947 PubMed:21815947] | ||
<pubmed>11274110,, </pubmed> | <pubmed>11274110,, </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 19:16, 19 November 2011
- Description: Na+/H+ antiporter
| Gene name | nhaC |
| Synonyms | yheL |
| Essential | no |
| Product | Na+/H+ antiporter |
| Function | pH homeostasis |
| MW, pI | 47 kDa, 7.874 |
| Gene length, protein length | 1359 bp, 453 aa |
| Immediate neighbours | dat, nhaX |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), pH homeostasis, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU09680
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: nhaC Na(+)/H(+) antiporter family (according to Swiss-Prot)
- Paralogous protein(s): MleN
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: O07553
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y. Mol Microbiol. 2011 81(6): 1459-1473. PubMed:21815947
Z Prágai, C Eschevins, S Bron, C R Harwood
Bacillus subtilis NhaC, an Na+/H+ antiporter, influences expression of the phoPR operon and production of alkaline phosphatases.
J Bacteriol: 2001, 183(8);2505-15
[PubMed:11274110]
[WorldCat.org]
[DOI]
(P p)
