Difference between revisions of "DnaN"
Line 55: | Line 55: | ||
=== Additional information=== | === Additional information=== | ||
− | |||
− | |||
− | |||
=The protein= | =The protein= | ||
Line 89: | Line 86: | ||
** DnaN forms dimers {{PubMed|16045613}} | ** DnaN forms dimers {{PubMed|16045613}} | ||
− | * '''Localization:''' | + | * '''Localization:''' |
+ | ** nucleoid (mid-cell spot) [http://www.ncbi.nlm.nih.gov/sites/entrez/9822387 PubMed] [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed] | ||
+ | ** forms large assemblies on DNA, called "clamp zones" {{PubMed|21419346}} | ||
=== Database entries === | === Database entries === | ||
Line 140: | Line 139: | ||
<pubmed> 20157337 </pubmed> | <pubmed> 20157337 </pubmed> | ||
==Original publications== | ==Original publications== | ||
+ | '''Additional publications:''' {{PubMed|21419346}} | ||
<pubmed>16942601 9822387 14651647,2987848 2168872 14651647 12060778 16461910, 16479537 19737352 19081080 11395445 20122408 20451384 15469515 16045613 </pubmed> | <pubmed>16942601 9822387 14651647,2987848 2168872 14651647 12060778 16461910, 16479537 19737352 19081080 11395445 20122408 20451384 15469515 16045613 </pubmed> | ||
'''Additional publications:''' {{PubMed|21050827}} | '''Additional publications:''' {{PubMed|21050827}} | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 08:04, 23 March 2011
- Description: DNA polymerase III (beta subunit), beta clamp, part of the replisome, also involved in DNA mismatch repair
Gene name | dnaN |
Synonyms | dnaG, dnaK |
Essential | yes PubMed |
Product | DNA polymerase III (beta subunit), beta clamp |
Function | DNA replication, DNA repair |
MW, pI | 41 kDa, 4.718 |
Gene length, protein length | 1134 bp, 378 aa |
Immediate neighbours | dnaA, yaaA |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
Categories containing this gene/protein
DNA replication, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00020
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1) (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P05649
- KEGG entry: [3]
- E.C. number: 2.7.7.7
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Philippe Noirot, Jouy-en-Josas, France homepage
Your additional remarks
References
Reviews
Tsutomu Katayama, Shogo Ozaki, Kenji Keyamura, Kazuyuki Fujimitsu
Regulation of the replication cycle: conserved and diverse regulatory systems for DnaA and oriC.
Nat Rev Microbiol: 2010, 8(3);163-70
[PubMed:20157337]
[WorldCat.org]
[DOI]
(I p)
Original publications
Additional publications: PubMed
Additional publications: PubMed