Difference between revisions of "SrfAB"
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| + | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[miscellaneous metabolic pathways]]}}, | ||
| + | {{SubtiWiki category|[[biosynthesis of antibacterial compounds]]}}, | ||
| + | {{SubtiWiki category|[[membrane proteins]]}}, | ||
| + | {{SubtiWiki category|[[phosphoproteins]]}} | ||
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| + | = This gene is a member of the following [[regulons]] = | ||
| + | {{SubtiWiki regulon|[[CodY regulon]]}}, | ||
| + | {{SubtiWiki regulon|[[ComA regulon]]}}, | ||
| + | {{SubtiWiki regulon|[[PerR regulon]]}}, | ||
| + | {{SubtiWiki regulon|[[Spx regulon]]}} | ||
=The gene= | =The gene= | ||
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=The protein= | =The protein= | ||
Revision as of 16:38, 8 December 2010
- Description: surfactin synthetase / competence
| Gene name | srfAB |
| Synonyms | comL |
| Essential | no |
| Product | surfactin synthetase / competence |
| Function | antibiotic synthesis |
| MW, pI | 400 kDa, 4.903 |
| Gene length, protein length | 10761 bp, 3587 aa |
| Immediate neighbours | srfAA, comS |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
miscellaneous metabolic pathways, biosynthesis of antibacterial compounds, membrane proteins, phosphoproteins
This gene is a member of the following regulons
CodY regulon, ComA regulon, PerR regulon, Spx regulon
The gene
Basic information
- Locus tag: BSU03490
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: ATP-dependent AMP-binding enzyme family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylation on Ser-999 AND Ser-2045 PubMed
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: membrane PubMed
Database entries
- Structure:
- UniProt: Q04747
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Massimiliano Marvasi, Pieter T Visscher, Lilliam Casillas Martinez
Exopolymeric substances (EPS) from Bacillus subtilis: polymers and genes encoding their synthesis.
FEMS Microbiol Lett: 2010, 313(1);1-9
[PubMed:20735481]
[WorldCat.org]
[DOI]
(I p)
Original publications
