Difference between revisions of "T-box"
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* Induction by threonine limitation | * Induction by threonine limitation | ||
| − | ** ''[[thrS]], [[thrZ]]'' | + | ** ''[[thrS]], [[thrZ]]-[[ywhA]]'' |
* Induction by tryptophan limitation | * Induction by tryptophan limitation | ||
Revision as of 20:14, 3 February 2010
The T-box element is an RNA switch that controls genes involved in amino acid metabolism.
In the absence of an amino acid, the uncharged tRNA binds the T-box region in the leader region of the mRNA of the controlled gene/ operon and thereby prevents the formation of a transcription terminator. The result is gene expression of the target gene in the absence of the specific amino acid.
Complete list of genes controlled by T-box elements
- Induction by alanine limitation
- Induction by serine limitation
Structure of a T-box ribowsitch
Melinda S Gerdeman, Tina M Henkin, Jennifer V Hines
Solution structure of the Bacillus subtilis T-box antiterminator RNA: seven nucleotide bulge characterized by stacking and flexibility.
J Mol Biol: 2003, 326(1);189-201
[PubMed:12547201]
[WorldCat.org]
[DOI]
(P p)
Reviews on T-box regulation
