Difference between revisions of "SdpI"
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| − | * '''Description:''' immunity protein, protection against SdpC <br/><br/> | + | * '''Description:''' immunity protein, protection against [[SdpC]] <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Product''' || immunity protein | |style="background:#ABCDEF;" align="center"| '''Product''' || immunity protein | ||
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| − | |style="background:#ABCDEF;" align="center"|'''Function''' || protection against SdpC | + | |style="background:#ABCDEF;" align="center"|'''Function''' || protection against [[SdpC]] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 23 kDa, 9.61 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 23 kDa, 9.61 | ||
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* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
| − | * '''Effectors of protein activity:''' | + | * '''Effectors of protein activity:''' in the presence of extracellular [[SdpC]], [[SdpI]] binds and sequesters [[SdpR]] , this results in induction of the ''[[sdpR]]-[[sdpI]]'' operon {{PubMed|16469701}} |
| − | * '''Interactions:''' | + | * '''Interactions:''' [[SdpI]]-[[SdpR]] {{PubMed|16469701}} |
* '''Localization:''' membrane (according to Swiss-Prot) | * '''Localization:''' membrane (according to Swiss-Prot) | ||
Revision as of 10:49, 29 December 2009
- Description: immunity protein, protection against SdpC
| Gene name | sdpI |
| Synonyms | yvaZ |
| Essential | no |
| Product | immunity protein |
| Function | protection against SdpC |
| MW, pI | 23 kDa, 9.61 |
| Gene length, protein length | 621 bp, 207 aa |
| Immediate neighbours | sdpC, sdpR |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU33780
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): YfhL
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: in the presence of extracellular SdpC, SdpI binds and sequesters SdpR , this results in induction of the sdpR-sdpI operon PubMed
- Localization: membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: O32241
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Craig D Ellermeier, Errett C Hobbs, Jose E Gonzalez-Pastor, Richard Losick
A three-protein signaling pathway governing immunity to a bacterial cannibalism toxin.
Cell: 2006, 124(3);549-59
[PubMed:16469701]
[WorldCat.org]
[DOI]
(P p)
José E González-Pastor, Errett C Hobbs, Richard Losick
Cannibalism by sporulating bacteria.
Science: 2003, 301(5632);510-3
[PubMed:12817086]
[WorldCat.org]
[DOI]
(I p)
