Difference between revisions of "CitS"

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(The protein)
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:''' ATP + protein L-histidine = ADP + protein N-phospho-L-histidine (according to Swiss-Prot)
+
* '''Catalyzed reaction/ biological activity:''' autophosphorylation, phosphorylation of [[CitT]]
  
 
* '''Protein family:'''
 
* '''Protein family:'''
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* '''Domains:''' two transmembrane segments, C-terminal histidine phosphotransferase domain
 
* '''Domains:''' two transmembrane segments, C-terminal histidine phosphotransferase domain
  
* '''Modification:'''
+
* '''Modification:''' autophosphorylation on a His residue
  
 
* '''Cofactor(s):'''
 
* '''Cofactor(s):'''
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:'''
+
* '''Interactions:''' [[CitS]]-[[CitT]]
  
 
* '''Localization:''' cell membrane (according to Swiss-Prot),  Membrane (Heterogeneous) [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed]
 
* '''Localization:''' cell membrane (according to Swiss-Prot),  Membrane (Heterogeneous) [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed]

Revision as of 20:08, 30 November 2009

  • Description: two-component sensor kinase, regulation of citrate uptake

Gene name citS
Synonyms yflR
Essential no
Product two-component sensor kinase
Function regulation of citrate uptake
Metabolic function and regulation of this protein in SubtiPathways:
Central C-metabolism
MW, pI 59 kDa, 6.481
Gene length, protein length 1626 bp, 542 aa
Immediate neighbours yflS, citT
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
CitS context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU07580

Phenotypes of a mutant

no growth with citrate as sole carbon source PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of CitT
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain
  • Modification: autophosphorylation on a His residue
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cell membrane (according to Swiss-Prot), Membrane (Heterogeneous) PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References