Difference between revisions of "RbsR"

From SubtiWiki
Jump to: navigation, search
Line 89: Line 89:
  
 
=Expression and regulation=
 
=Expression and regulation=
 +
* '''Operon:''' ''[[rbsR]]-[[rbsK]]-[[rbsD]]-[[rbsA]]-[[rbsC]]-[[rbsB]]'' {{PubMed|7921236}}
  
* '''Operon:''' ''[[rbsR]]-[[rbsK]]-[[rbsD]]-[[rbsA]]-[[rbsC]]-[[rbsB]]''
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|7511775}}
  
* '''[[Sigma factor]]:''' [[SigA]]
+
* '''Regulation:'''  
 
+
** repressed by glucose (10-fold) ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed]   
* '''Regulation:''' repressed by glucose (10-fold) ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed]   
 
 
** expressed upon transition into the stationary phase ([[AbrB]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/7592460 PubMed]
 
** expressed upon transition into the stationary phase ([[AbrB]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/7592460 PubMed]
  
* '''Regulatory mechanism:''' [[CcpA]]: transcription repression  
+
* '''Regulatory mechanism:'''  
 +
** [[CcpA]]: transcription repression {{PubMed|7921236}}
 
** [[AbrB]]:  transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/7592460 PubMed]
 
** [[AbrB]]:  transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/7592460 PubMed]
  
Line 122: Line 123:
 
=References=
 
=References=
  
<pubmed>16872404,16519689,,7592460,12850135 7921236 16519689, </pubmed>
+
<pubmed>16872404,16519689,,7592460,12850135 7921236 7511775 , </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 11:01, 9 January 2010

  • Description: transcriptional repressor of the ribose operon

Gene name rbsR
Synonyms
Essential no
Product transcriptional repressor (LacI family)
Function regulation of ribose utilization
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism
MW, pI 35 kDa, 5.577
Gene length, protein length 978 bp, 326 aa
Immediate neighbours capB, rbsK
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RbsR context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU35910

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed by glucose (10-fold) (CcpA) PubMed
    • expressed upon transition into the stationary phase (AbrB) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References