Difference between revisions of "YveA"
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=Expression and regulation= | =Expression and regulation= | ||
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* '''Operon:''' | * '''Operon:''' | ||
| + | ** ''[[sacB]]-[[levB]]-[[yveA]]'' {{PubMed|11739774}} | ||
| + | ** ''[[yveA]]'' {{PubMed|16497325}} | ||
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
| + | ** ''[[sacB]]'': [[SigA]] {{PubMed|2428811}} | ||
** ''yveA'': [[SigG]] {{PubMed|16497325}} | ** ''yveA'': [[SigG]] {{PubMed|16497325}} | ||
| − | * '''Regulation:''' expressed during sporulation in the forespore ([[SigG]]) {{PubMed|16497325}} | + | * '''Regulation:''' |
| + | ** induction by sucrose (at high concentration) ([[SacY]]) {{PubMed|3039303}} | ||
| + | ** expressed during sporulation in the forespore ([[SigG]]) {{PubMed|16497325}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[SacY]]: binding to a [[RNA switch]] (transcriptional antitermination) {{PubMed|3039303}} | ||
| + | ** [[DegU]]-P: transcription activation {{PubMed|2428811}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 118: | Line 124: | ||
=References= | =References= | ||
| − | <pubmed>12730183 | + | <pubmed>12730183 11739774 2428811 3039303 16497325</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 11:12, 30 December 2009
- Description: aspartate/ glutamate transporter
| Gene name | yveA |
| Synonyms | |
| Essential | no |
| Product | aspartate/ glutamate transporter |
| Function | aspartate uptake |
| MW, pI | 56 kDa, 9.675 |
| Gene length, protein length | 1560 bp, 520 aa |
| Immediate neighbours | levB, yvdT |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU34470
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): YbeC
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: O07002
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- SacY: binding to a RNA switch (transcriptional antitermination) PubMed
- DegU-P: transcription activation PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Stephanie T Wang, Barbara Setlow, Erin M Conlon, Jessica L Lyon, Daisuke Imamura, Tsutomu Sato, Peter Setlow, Richard Losick, Patrick Eichenberger
The forespore line of gene expression in Bacillus subtilis.
J Mol Biol: 2006, 358(1);16-37
[PubMed:16497325]
[WorldCat.org]
[DOI]
(P p)
Graciela Lorca, Brit Winnen, Milton H Saier
Identification of the L-aspartate transporter in Bacillus subtilis.
J Bacteriol: 2003, 185(10);3218-22
[PubMed:12730183]
[WorldCat.org]
[DOI]
(P p)
Y Pereira, M F Petit-Glatron, R Chambert
yveB, Encoding endolevanase LevB, is part of the sacB-yveB-yveA levansucrase tricistronic operon in Bacillus subtilis.
Microbiology (Reading): 2001, 147(Pt 12);3413-9
[PubMed:11739774]
[WorldCat.org]
[DOI]
(P p)
S Aymerich, M Steinmetz
Cloning and preliminary characterization of the sacS locus from Bacillus subtilis which controls the regulation of the exoenzyme levansucrase.
Mol Gen Genet: 1987, 208(1-2);114-20
[PubMed:3039303]
[WorldCat.org]
[DOI]
(P p)
H Shimotsu, D J Henner
Modulation of Bacillus subtilis levansucrase gene expression by sucrose and regulation of the steady-state mRNA level by sacU and sacQ genes.
J Bacteriol: 1986, 168(1);380-8
[PubMed:2428811]
[WorldCat.org]
[DOI]
(P p)
