Difference between revisions of "DhbA"

From SubtiWiki
Jump to: navigation, search
Line 90: Line 90:
 
=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''[[dhbA]]-[[dhbC]]-[[dhbE]]-[[dhbB]]-[[dhbF]]'' {{PubMed|8921902}}
  
* '''[[Sigma factor]]:'''  
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|8550523}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
** repressed unless the cells enter an iron starvation ([[Fur]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12354229 PubMed]
+
** induced by iron starvation ([[Fur]]) {{PubMed|12354229}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
** [[Fur]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12354229 PubMed]
+
** [[Fur]]: transcription repression {{PubMed|12354229}}
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
Line 122: Line 122:
 
=References=
 
=References=
  
<pubmed>8224884,10400588,,11790741,12354229, </pubmed>
+
<pubmed>8224884,10400588,,11790741,12354229, 8921902 8550523</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 10:51, 10 October 2009

  • Description: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

Gene name dhbA
Synonyms entA
Essential no
Product 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
Function siderophore biosynthesis
MW, pI 27 kDa, 5.311
Gene length, protein length 783 bp, 261 aa
Immediate neighbours dhbC, besA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
DhbA context.gif
This image was kindly provided by SubtiList





The gene

Basic information

  • Locus tag: BSU32000

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 2,3-dihydro-2,3-dihydroxybenzoate + NAD+ = 2,3-dihydroxybenzoate + NADH (according to Swiss-Prot)
  • Protein family: short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References