Difference between revisions of "AcuC"

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* '''Description:''' protein deacetylase for the control of AcsA activity <br/><br/>
+
* '''Description:''' protein deacetylase for the control of [[AcsA]] activity <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || AcsA deacetylase
+
|style="background:#ABCDEF;" align="center"| '''Product''' || [[AcsA]] deacetylase
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || control of AcsA activity  
+
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[AcsA]] activity  
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 5.062   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 5.062   
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=Expression and regulation=
 
=Expression and regulation=
 +
* '''Operon:''' ''[[acuA]]-[[acuB]]-[[acuC]]'' {{PubMed|7934817}}
  
* '''Operon:'''
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|7913927}}
 
 
* '''[[Sigma factor]]:'''  
 
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** repressed by glucose ([[CcpA]]) {{PubMed|7913927,12850135}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[CcpA]]: transcription repression {{PubMed|7913927}}
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  

Revision as of 11:39, 19 December 2009

  • Description: protein deacetylase for the control of AcsA activity

Gene name acuC
Synonyms
Essential no
Product AcsA deacetylase
Function control of AcsA activity
MW, pI 42 kDa, 5.062
Gene length, protein length 1161 bp, 387 aa
Immediate neighbours acuB, motS
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
AcuC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU29710

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: deacetylates (and thereby activates) AcsA (together with SrtN) PubMed
  • Protein family: histone deacetylase family (according to Swiss-Prot) class I histone deacetylase
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References