Difference between revisions of "TrxA"
| Line 92: | Line 92: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''trxA'' {{PubMed|9537387}} |
| − | * '''[[Sigma factor]]:''' [[SigB]] | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|9537387}}, [[SigB]] {{PubMed|9537387,11544224}} |
| − | * '''Regulation:''' induced by stress ([[SigB]]) [http://www.ncbi.nlm.nih.gov/pubmed/11544224 PubMed | + | * '''Regulation:''' |
| + | ** induced by stress ([[SigB]]) [http://www.ncbi.nlm.nih.gov/pubmed/11544224 PubMed] | ||
| + | ** regulation by [[Spx]] in response to diamide stress | ||
| + | ** induced by heat stress ([[CtsR]]) {{PubMed|9852015}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[CtsR]]: transcription repression {{PubMed|9852015}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 122: | Line 126: | ||
=References= | =References= | ||
| − | <pubmed>9537387,15937154,18601268,18456801,,11544224,18687074 </pubmed> | + | <pubmed>9537387,15937154,18601268,18456801,9852015 ,11544224,18687074 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 21:07, 14 December 2009
- Description: antioxidative action by facilitating the reduction of other proteins by cysteine thiol-disulfide exchange
| Gene name | trxA |
| Synonyms | trx |
| Essential | yes PubMed |
| Product | thioredoxin |
| Function | protection of proteins against oxidative damage |
| MW, pI | 11 kDa, 4.308 |
| Gene length, protein length | 312 bp, 104 aa |
| Immediate neighbours | uvrC, abf2 |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU28500
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: thioredoxin family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- UniProt: P14949
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: trxA PubMed
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
