Difference between revisions of "BacF"
| Line 1: | Line 1: | ||
| − | * '''Description:''' | + | * '''Description:''' aspartate aminotransferase involved in bacilysin synthesis<br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Gene name''' | |style="background:#ABCDEF;" align="center"|'''Gene name''' | ||
| − | |'' | + | |''bacF'' |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ipa-85d '' | + | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ywfG, ipa-85d '' |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || aspartate aminotransferase |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of the antibiotic bacilysin |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 44 kDa, 5.347 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 44 kDa, 5.347 | ||
| Line 88: | Line 88: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[bacA]]-[[bacB]]-[[bacC]]-[[bacD]]-[[bacE]]-[[bacF]]'' {{PubMed|12372825}} |
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
| Line 95: | Line 95: | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[CodY]]: transcription repression {{PubMed|12372825}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 117: | Line 118: | ||
=References= | =References= | ||
| + | <pubmed> 12372825 </pubmed> | ||
Revision as of 21:24, 9 July 2009
- Description: aspartate aminotransferase involved in bacilysin synthesis
| Gene name | bacF |
| Synonyms | ywfG, ipa-85d |
| Essential | no |
| Product | aspartate aminotransferase |
| Function | biosynthesis of the antibiotic bacilysin |
| MW, pI | 44 kDa, 5.347 |
| Gene length, protein length | 1197 bp, 399 aa |
| Immediate neighbours | ywfH, bacE |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU37690
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate (according to Swiss-Prot)
- Protein family: class-I pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- Swiss prot entry: P39643
- KEGG entry: [2]
- E.C. number: 2.6.1.1
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
