Difference between revisions of "S-box Element"

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The s-box element is a [[riboswitch]] that controls different genes within the sulfur metabolism.
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The S-box element is a [[riboswitch]] that controls different genes of sulphur metabolism in  response to the presence of S-adenosylmethionine.
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* Upon binding of SAM, the [[riboswitch]] adopts a terminator structure resulting in transcription termination.
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* In the absence of SAM, the [[riboswitch]] has the antitermination structure that allows transcription elongation into the controlled gene/ operon.
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* S-box riboswitch turnover is initiated by [[rny |RNase Y]]  {{PubMed|19779461}}
  
Genes controled by s-box element:
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==Genes controlled by a S-box==
*[[cysH]],
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* ''[[cysH]]-[[cysP]]-[[sat]]-[[cysC]]-[[ylnD]]-[[ylnE]]-[[ylnF]]''
*[[metE]],
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* ''[[metE]]''
*[[metK]],
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* ''[[metI]]''-''[[metC]]''
*[[yitJ]],
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* ''[[metK]]''
*[[yjcI]],
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* ''[[metN]]-[[metP]]-[[metQ]]''
*[[ykrT]],
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* ''[[mtnK]]-[[mtnA]]''
*[[ykrW]],
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* ''[[mtnW]]-[[mtnX]]-[[mtnB]]-[[mtnD]]''
*[[yoaD]],
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* ''[[yitJ]]-[[yitI]]-[[yitH]]''
*[[yusC]],
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* ''[[yoaD]]-[[yoaC]]-[[yoaB]]''
*[[yxjG]],
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* ''[[yxjG]]''
*[[yxjH]]
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* ''[[yxjH]]''
  
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==References==
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<pubmed> 18039762,12626738 ,17381302 19779461 12787499 18039762 18443629 20951706 22543867 28701520</pubmed>
  
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=See also:=
# Tomsic J, McDaniel BA, Grundy FJ, (2008) Henkin TM. Natural variability in S-adenosylmethionine (SAM)-dependent riboswitches: S-box elements in bacillus subtilis exhibit differential sensitivity to SAM In vivo and in vitro. J Bacteriol. '''Feb;190(3):''' 823-33. [http://www.ncbi.nlm.nih.gov/sites/entrez/18039762PubMed]
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* [[RNA switch]]
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=Back to [[regulons]]=

Latest revision as of 09:03, 14 July 2017

The S-box element is a riboswitch that controls different genes of sulphur metabolism in response to the presence of S-adenosylmethionine.

  • Upon binding of SAM, the riboswitch adopts a terminator structure resulting in transcription termination.
  • In the absence of SAM, the riboswitch has the antitermination structure that allows transcription elongation into the controlled gene/ operon.
  • S-box riboswitch turnover is initiated by RNase Y PubMed

Genes controlled by a S-box

References


See also:

Back to regulons