Difference between revisions of "Replisome"

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(In vitro reconstitution of the replisome)
 
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==''In vitro'' reconstitution of the replisome==
 
==''In vitro'' reconstitution of the replisome==
<pubmed> 20122408 </pubmed>
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<pubmed> 20122408 35635709 </pubmed>
  
 
==Reviews==
 
==Reviews==
<pubmed>26097470 16036556 21675919</pubmed>
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<pubmed>26097470 16036556 21675919,29856930 </pubmed>
  
 
==Other important publications==
 
==Other important publications==
 
<pubmed> 21350489 21419346</pubmed>
 
<pubmed> 21350489 21419346</pubmed>

Latest revision as of 10:54, 20 June 2022

The replisome is a protein complex that is required and sufficient for replication of both leading and lagging strands.

PolC-HolA-HolB-DnaX-DnaN-DnaG-DnaC-DnaI-DnaD-SsbA-DnaE-PriA-DnaB PubMed

RecA colocalizes to the replisome in response to endogenous and exogenous DNA damage and in response to damage-independent fork arrest (formation of DNA repair centers), repair center formation depends on RecO and RecR, and is facilitated by RecF and SsbA PubMed

Related pages

Back to Protein-protein interactions

In vitro reconstitution of the replisome

Hannah Gaimster, Charles Winterhalter, Alan Koh, Heath Murray
Visualizing the Replisome, Chromosome Breaks, and Replication Restart in Bacillus subtilis.
Methods Mol Biol: 2022, 2476;263-276
[PubMed:35635709] [WorldCat.org] [DOI] (I p)

Glenn M Sanders, H Garry Dallmann, Charles S McHenry
Reconstitution of the B. subtilis replisome with 13 proteins including two distinct replicases.
Mol Cell: 2010, 37(2);273-81
[PubMed:20122408] [WorldCat.org] [DOI] (I p)


Reviews


Other important publications

Masayuki Su'etsugu, Jeff Errington
The replicase sliding clamp dynamically accumulates behind progressing replication forks in Bacillus subtilis cells.
Mol Cell: 2011, 41(6);720-32
[PubMed:21419346] [WorldCat.org] [DOI] (I p)

Houra Merrikh, Cristina Machón, William H Grainger, Alan D Grossman, Panos Soultanas
Co-directional replication-transcription conflicts lead to replication restart.
Nature: 2011, 470(7335);554-7
[PubMed:21350489] [WorldCat.org] [DOI] (I p)