Difference between revisions of "Fla-che operon"

From SubtiWiki
Jump to: navigation, search
 
(4 intermediate revisions by the same user not shown)
Line 1: Line 1:
 
The [[fla-che operon]] encodes major factors required for [[motility and chemotaxis]]
 
The [[fla-che operon]] encodes major factors required for [[motility and chemotaxis]]
  
−
* ''[[flgB]]-[[flgC]]-[[fliE]]-[[fliF]]-[[fliG]]-[[fliH]]-[[fliI]]-[[fliJ]]-[[ylxF]]-[[fliK]]-[[flgD]]-[[flgE]]-[[fliL]]-[[fliM]]-[[fliY]]-[[cheY]]-[[fliZ]]-[[fliP]]-[[fliQ]]-[[fliR]]-[[flhB]]-[[flhA]]-[[flhF]]-[[flhG]]-[[cheB]]-[[cheA]]-[[cheW]]-[[cheC]]-[[cheD]]-[[sigD]]-[[swrB]]'' {{PubMed|9657996,8157612,15175317}}
+
* The operon is expressed from promoters upstream of ''[[flgB]]'', ''[[ylxF]]'', and ''[[sigD]]'':
 +
** ''[[flgB]]-[[flgC]]-[[fliE]]-[[fliF]]-[[fliG]]-[[fliH]]-[[fliI]]-[[fliJ]]-[[ylxF]]-[[fliK]]-[[flgD]]-[[flgE]]-[[fliL]]-[[fliM]]-[[fliY]]-[[cheY]]-[[fliZ]]-[[fliP]]-[[fliQ]]-[[fliR]]-[[flhB]]-[[flhA]]-[[flhF]]-[[flhG]]-[[cheB]]-[[cheA]]-[[cheW]]-[[cheC]]-[[cheD]]-[[sigD]]-[[swrB]]'' {{PubMed|9657996,8157612,15175317}}
 +
** ''[[ylxF]]-[[fliK]]-[[flgD]]-[[flgE]]-[[fliL]]-[[fliM]]-[[fliY]]-[[cheY]]-[[fliZ]]-[[fliP]]-[[fliQ]]-[[fliR]]-[[flhB]]-[[flhA]]-[[flhF]]-[[flhG]]-[[cheB]]-[[cheA]]-[[cheW]]-[[cheC]]-[[cheD]]-[[sigD]]-[[swrB]]'' {{PubMed|20233303}}
 +
** ''[[sigD]]-[[swrB]]'' {{PubMed|9335309}}
  
−
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|9657996}}, [[SigD]] {{PubMed|9657996}}
+
* '''[[Sigma factor]]:'''
 +
** ''[[flgB]]'': [[SigA]] {{PubMed|9657996}}, [[SigD]] {{PubMed|9657996}}
 +
** ''[[ylxF]]'': [[SigD]] {{PubMed|20233303}}
 +
** ''[[sigD]]'': [[SigA]] {{PubMed|9335309}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
−
** repressed under conditions that trigger sporulation ([[Spo0A]]) {{PubMed|14651647}}
+
** repressed under conditions that trigger sporulation ([[Spo0A]]) {{PubMed|14651647}}
 +
** reduced expression in the absence of [[PnpA]] (due to accumulation of [[SlrA]]) {{PubMed|26857544}}  
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
Line 14: Line 21:
 
** [[DegU]]-P: transcription repression {{PubMed|24386445}}
 
** [[DegU]]-P: transcription repression {{PubMed|24386445}}
 
** [[DegU]]-P in complex with [[SwrA]]: transcription activation {{PubMed|24386445}}
 
** [[DegU]]-P in complex with [[SwrA]]: transcription activation {{PubMed|24386445}}
 +
 +
=== Important publications on the expression and regulation of the ''fla-che'' operon ===
 +
<pubmed> 26170408, 26857544 </pubmed>
 +
== Back to [[operons]] ==

Latest revision as of 14:43, 8 October 2017

The fla-che operon encodes major factors required for motility and chemotaxis

  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
    • reduced expression in the absence of PnpA (due to accumulation of SlrA) PubMed

Important publications on the expression and regulation of the fla-che operon

Bo Liu, Daniel B Kearns, David H Bechhofer
Expression of multiple Bacillus subtilis genes is controlled by decay of slrA mRNA from Rho-dependent 3' ends.
Nucleic Acids Res: 2016, 44(7);3364-72
[PubMed:26857544] [WorldCat.org] [DOI] (I p)

Qutaiba O Ababneh, Jennifer K Herman
CodY Regulates SigD Levels and Activity by Binding to Three Sites in the fla/che Operon.
J Bacteriol: 2015, 197(18);2999-3006
[PubMed:26170408] [WorldCat.org] [DOI] (I p)

Back to operons

Retrieved from "http://subtiwiki-test.uni-goettingen.de/wiki//index.php?title=Fla-che_operon&oldid=209796"