Difference between revisions of "Transport proteins"

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* Channel of large conductance: [[MscL]]
 
* Channel of large conductance: [[MscL]]
 
* Channels of small conductance: [[YfkC]], [[YhdY]], [[YkuT]]
 
* Channels of small conductance: [[YfkC]], [[YhdY]], [[YkuT]]
 +
* Channel implicated in [[sporulation]]: [[SpoVAC]]
 +
** a mutant devoid of all four mechanosensitive channels (TMB99, Δ(''[[mscL]]''::''spc'') Δ(''[[ykuT]]''::''cat'')  Δ(''[[yhdY]]''::''ery'') Δ(''[[yfkC]]''::''kan'')) is available in [[Erhard Bremer]]'s lab {{PubMed|22685134}}
  
 
=Ion transporters=
 
=Ion transporters=
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* Na(+)/H(+) antiporter: [[MrpA]]-[[MrpB]]-[[MrpC]]-[[MrpD]]-[[MrpE]]-[[MrpF]]-[[MrpG]]
 
* Na(+)/H(+) antiporter: [[MrpA]]-[[MrpB]]-[[MrpC]]-[[MrpD]]-[[MrpE]]-[[MrpF]]-[[MrpG]]
 
* monovalent cation (Na, K, Li, Rb)/H(+) antiporter: [[NhaK]]
 
* monovalent cation (Na, K, Li, Rb)/H(+) antiporter: [[NhaK]]
 +
 +
= ECF transporter for the uptake of micronutrients =
 +
* ([[YbxA]]-[[YbaE]])-[[YbaF]] (general components)
 +
* [[RibU]]
 +
* [[ThiT]]
 +
* [[YhfU]]
 +
* [[TrpP]]
  
 
=Amino acid uptake=
 
=Amino acid uptake=
 
* arginine: [[ArtP]]-[[ArtQ]]-[[ArtR]]
 
* arginine: [[ArtP]]-[[ArtQ]]-[[ArtR]]
 +
* branched-chain amino acids: [[BraB]], [[BrnQ]]
 
* cystine: [[TcyA]]-[[TcyB]]-[[TcyC]]; [[TcyJ]]-[[TcyK]]-[[TcyL]]-[[TcyM]]-[[TcyN]]
 
* cystine: [[TcyA]]-[[TcyB]]-[[TcyC]]; [[TcyJ]]-[[TcyK]]-[[TcyL]]-[[TcyM]]-[[TcyN]]
 
* glutamate: [[GltP]]; [[GltP]]
 
* glutamate: [[GltP]]; [[GltP]]
 
* glutamine: [[GlnH]]-[[GlnM]]-[[GlnP]]-[[GlnQ]]
 
* glutamine: [[GlnH]]-[[GlnM]]-[[GlnP]]-[[GlnQ]]
 +
* lysine: [[YvsH]]
 
* methionine: [[MetN]]-[[MetP]]-[[MetQ]]
 
* methionine: [[MetN]]-[[MetP]]-[[MetQ]]
* proline: [[YcgO]]
+
* proline: [[PutP]]
 +
* tryptophan: ([[YbxA]]-[[YbaE]])-[[YbaF]]-[[TrpP]]
 +
 
 +
=Nucleotide and nucleoside transporters=
 +
==Nucleotide and nucleoside uptake==
 +
* hypoxanthine/ guanine: [[PbuG]]
 +
* hypoxanthine/ guanine: [[PbuO]] (based on similarity)
 +
 
 +
==Nucleotide and nucleoside export==
 +
* hypoxanthine: [[PbuE]] (putative)
  
 
=Sugar transport proteins=
 
=Sugar transport proteins=
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* aminosugar uptake: [[YurJ]]-[[YurM]]-[[YurN]]-[[YurO]]
 
* aminosugar uptake: [[YurJ]]-[[YurM]]-[[YurN]]-[[YurO]]
 
* arabinose uptake: [[AraN]]-[[AraP]]-[[AraQ]]
 
* arabinose uptake: [[AraN]]-[[AraP]]-[[AraQ]]
* cyclodextrin/maltodextrin (probably): [[CycB]], [[YvfL]], [[YvfM]]
+
* galactotriose uptake: [[CycB]]-[[GanP]]-[[GanQ]]
 
* maltodextrin uptake: [[MdxE]]-[[MdxF]]-[[MdxG]]
 
* maltodextrin uptake: [[MdxE]]-[[MdxF]]-[[MdxG]]
 
* melibiose uptake: [[AmyC]]-[[AmyD]]-[[MsmE]]
 
* melibiose uptake: [[AmyC]]-[[AmyD]]-[[MsmE]]
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=Relevant Reviews=
 
=Relevant Reviews=
<pubmed>10627040 10092453  12626684 </pubmed>
+
<pubmed>10627040 10092453  12626684 11763970 10627041 20825352 22685280 20497229 24258154 </pubmed>

Latest revision as of 17:51, 31 March 2014

Mechanosensitive channels

Ion transporters

Ion uptake

Ion export

ECF transporter for the uptake of micronutrients

Amino acid uptake

Nucleotide and nucleoside transporters

Nucleotide and nucleoside uptake

  • hypoxanthine/ guanine: PbuG
  • hypoxanthine/ guanine: PbuO (based on similarity)

Nucleotide and nucleoside export

  • hypoxanthine: PbuE (putative)

Sugar transport proteins

ABC transporters

PTS proteins

  • General PTS proteins: Enzyme I, HPr
  • PtsG: glucose permease, EIICBA
  • GamP: glucosamine permease, EIICBA
  • MurP: N-acetyl muramic acid-specific phosphotransferase system, EIIBC component
  • MtlA, MtlF: mannitol permease
  • GmuA, GmuB, GmuC: galactomannan permease
  • TreP: trehalose permease
  • MalP: maltose permease
  • FruA: fructose permease
  • ManP: mannose permease
  • YpqE: unknown EIIA component
  • LevD, LevE, LevF, LevG: fructose permease
  • SacP: sucrose permease (high affinity)
  • SacY: sucrose permease (low affinity)
  • LicA, LicB, LicC: lichenan permease
  • BglP: ß-glucoside permease
  • YyzE: unknown PTS protein
  • YwbA: unknown EIIC component

The PTS in SubtiPathways

Transporters for the uptake of compatible solutes in response to hyperosmolarity

Uptake of siderophores


Related Lists

External Links

The Transporter Classification Database

Relevant Reviews