Difference between revisions of "Transport proteins"
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* Channel of large conductance: [[MscL]] | * Channel of large conductance: [[MscL]] | ||
* Channels of small conductance: [[YfkC]], [[YhdY]], [[YkuT]] | * Channels of small conductance: [[YfkC]], [[YhdY]], [[YkuT]] | ||
+ | * Channel implicated in [[sporulation]]: [[SpoVAC]] | ||
+ | ** a mutant devoid of all four mechanosensitive channels (TMB99, Δ(''[[mscL]]''::''spc'') Δ(''[[ykuT]]''::''cat'') Δ(''[[yhdY]]''::''ery'') Δ(''[[yfkC]]''::''kan'')) is available in [[Erhard Bremer]]'s lab {{PubMed|22685134}} | ||
=Ion transporters= | =Ion transporters= | ||
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* monovalent cation (Na, K, Li, Rb)/H(+) antiporter: [[NhaK]] | * monovalent cation (Na, K, Li, Rb)/H(+) antiporter: [[NhaK]] | ||
− | =Amino acid | + | = ECF transporter for the uptake of micronutrients = |
− | * glutamate: [[GltP]] | + | * ([[YbxA]]-[[YbaE]])-[[YbaF]] (general components) |
− | * proline: [[ | + | * [[RibU]] |
+ | * [[ThiT]] | ||
+ | * [[YhfU]] | ||
+ | * [[TrpP]] | ||
+ | |||
+ | =Amino acid uptake= | ||
+ | * arginine: [[ArtP]]-[[ArtQ]]-[[ArtR]] | ||
+ | * branched-chain amino acids: [[BraB]], [[BrnQ]] | ||
+ | * cystine: [[TcyA]]-[[TcyB]]-[[TcyC]]; [[TcyJ]]-[[TcyK]]-[[TcyL]]-[[TcyM]]-[[TcyN]] | ||
+ | * glutamate: [[GltP]]; [[GltP]] | ||
+ | * glutamine: [[GlnH]]-[[GlnM]]-[[GlnP]]-[[GlnQ]] | ||
+ | * lysine: [[YvsH]] | ||
+ | * methionine: [[MetN]]-[[MetP]]-[[MetQ]] | ||
+ | * proline: [[PutP]] | ||
+ | * tryptophan: ([[YbxA]]-[[YbaE]])-[[YbaF]]-[[TrpP]] | ||
+ | |||
+ | =Nucleotide and nucleoside transporters= | ||
+ | ==Nucleotide and nucleoside uptake== | ||
+ | * hypoxanthine/ guanine: [[PbuG]] | ||
+ | * hypoxanthine/ guanine: [[PbuO]] (based on similarity) | ||
+ | |||
+ | ==Nucleotide and nucleoside export== | ||
+ | * hypoxanthine: [[PbuE]] (putative) | ||
=Sugar transport proteins= | =Sugar transport proteins= | ||
+ | ==ABC transporters== | ||
+ | * ATP-binding subunit for multiple [[ABC transporter]]s: [[MsmX]] | ||
+ | * aminosugar uptake: [[YurJ]]-[[YurM]]-[[YurN]]-[[YurO]] | ||
+ | * arabinose uptake: [[AraN]]-[[AraP]]-[[AraQ]] | ||
+ | * galactotriose uptake: [[CycB]]-[[GanP]]-[[GanQ]] | ||
+ | * maltodextrin uptake: [[MdxE]]-[[MdxF]]-[[MdxG]] | ||
+ | * melibiose uptake: [[AmyC]]-[[AmyD]]-[[MsmE]] | ||
+ | * ribose uptake: [[RbsA]]-[[RbsB]]-[[RbsC]]-[[RbsD]] | ||
+ | |||
==[[PTS]] proteins== | ==[[PTS]] proteins== | ||
* General [[PTS]] proteins: [[ptsI|Enzyme I]], [[ptsH|HPr]] | * General [[PTS]] proteins: [[ptsI|Enzyme I]], [[ptsH|HPr]] | ||
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* [[GamP]]: glucosamine permease, EIICBA | * [[GamP]]: glucosamine permease, EIICBA | ||
* [[MurP]]: N-acetyl muramic acid-specific phosphotransferase system, EIIBC component | * [[MurP]]: N-acetyl muramic acid-specific phosphotransferase system, EIIBC component | ||
− | * [[MtlA]]: mannitol permease | + | * [[MtlA]], [[MtlF]]: mannitol permease |
* [[GmuA]], [[GmuB]], [[GmuC]]: galactomannan permease | * [[GmuA]], [[GmuB]], [[GmuC]]: galactomannan permease | ||
* [[TreP]]: trehalose permease | * [[TreP]]: trehalose permease | ||
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* [[BglP]]: ß-glucoside permease | * [[BglP]]: ß-glucoside permease | ||
* [[YyzE]]: unknown PTS protein | * [[YyzE]]: unknown PTS protein | ||
− | |||
* [[YwbA]]: unknown EIIC component | * [[YwbA]]: unknown EIIC component | ||
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* [[OpuD]]: transporter for glycine betaine | * [[OpuD]]: transporter for glycine betaine | ||
* [[OpuE]]: transporter for proline | * [[OpuE]]: transporter for proline | ||
+ | |||
+ | ==Uptake of siderophores== | ||
+ | * petrobactin: [[YclN]]-[[YclO]]-[[YclP]]-[[YclQ]] | ||
+ | |||
=Related Lists= | =Related Lists= | ||
* [[ABC transporter]], [[PTS]] | * [[ABC transporter]], [[PTS]] | ||
+ | |||
+ | =External Links= | ||
+ | [http://www.tcdb.org/ The Transporter Classification Database] | ||
=Relevant Reviews= | =Relevant Reviews= | ||
− | <pubmed>10627040 </pubmed> | + | <pubmed>10627040 10092453 12626684 11763970 10627041 20825352 22685280 20497229 24258154 </pubmed> |
Latest revision as of 17:51, 31 March 2014
Contents
- 1 Mechanosensitive channels
- 2 Ion transporters
- 3 ECF transporter for the uptake of micronutrients
- 4 Amino acid uptake
- 5 Nucleotide and nucleoside transporters
- 6 Sugar transport proteins
- 7 Transporters for the uptake of compatible solutes in response to hyperosmolarity
- 8 Related Lists
- 9 External Links
- 10 Relevant Reviews
Mechanosensitive channels
- Channel of large conductance: MscL
- Channels of small conductance: YfkC, YhdY, YkuT
- Channel implicated in sporulation: SpoVAC
Ion transporters
Ion uptake
Ion export
- Na(+)/H(+) antiporter: MrpA-MrpB-MrpC-MrpD-MrpE-MrpF-MrpG
- monovalent cation (Na, K, Li, Rb)/H(+) antiporter: NhaK
ECF transporter for the uptake of micronutrients
Amino acid uptake
- arginine: ArtP-ArtQ-ArtR
- branched-chain amino acids: BraB, BrnQ
- cystine: TcyA-TcyB-TcyC; TcyJ-TcyK-TcyL-TcyM-TcyN
- glutamate: GltP; GltP
- glutamine: GlnH-GlnM-GlnP-GlnQ
- lysine: YvsH
- methionine: MetN-MetP-MetQ
- proline: PutP
- tryptophan: (YbxA-YbaE)-YbaF-TrpP
Nucleotide and nucleoside transporters
Nucleotide and nucleoside uptake
Nucleotide and nucleoside export
- hypoxanthine: PbuE (putative)
Sugar transport proteins
ABC transporters
- ATP-binding subunit for multiple ABC transporters: MsmX
- aminosugar uptake: YurJ-YurM-YurN-YurO
- arabinose uptake: AraN-AraP-AraQ
- galactotriose uptake: CycB-GanP-GanQ
- maltodextrin uptake: MdxE-MdxF-MdxG
- melibiose uptake: AmyC-AmyD-MsmE
- ribose uptake: RbsA-RbsB-RbsC-RbsD
PTS proteins
- General PTS proteins: Enzyme I, HPr
- PtsG: glucose permease, EIICBA
- GamP: glucosamine permease, EIICBA
- MurP: N-acetyl muramic acid-specific phosphotransferase system, EIIBC component
- MtlA, MtlF: mannitol permease
- GmuA, GmuB, GmuC: galactomannan permease
- TreP: trehalose permease
- MalP: maltose permease
- FruA: fructose permease
- ManP: mannose permease
- YpqE: unknown EIIA component
- LevD, LevE, LevF, LevG: fructose permease
- SacP: sucrose permease (high affinity)
- SacY: sucrose permease (low affinity)
- LicA, LicB, LicC: lichenan permease
- BglP: ß-glucoside permease
- YyzE: unknown PTS protein
- YwbA: unknown EIIC component
The PTS in SubtiPathways
Transporters for the uptake of compatible solutes in response to hyperosmolarity
- OpuAA-OpuAB-OpuAC: ABC transporter for glycine betaine
- OpuBA-OpuBB-OpuBC-OpuBD: ABC transporter for choline
- OpuCA-OpuCB-OpuCC-OpuCD: ABC transporter for glycine betaine/ carnitine/ choline
- OpuD: transporter for glycine betaine
- OpuE: transporter for proline
Uptake of siderophores
Related Lists
External Links
The Transporter Classification Database
Relevant Reviews