Difference between revisions of "S-box Element"
| Line 1: | Line 1: | ||
| − | The S-box element is a [[riboswitch]] that controls different genes of sulphur metabolism in response to the presence of S-adenosylmethionine. | + | The S-box element is a [[riboswitch]] that controls different genes of sulphur metabolism in response to the presence of S-adenosylmethionine. |
| + | * Upon binding of SAM, the [[riboswitch]] adopts a terminator structure resulting in transcription termination. | ||
| + | * In the aabsence of SAM, the [[riboswitch]] has the antitermination structure that allows transcription elongation into the controlled gene/ operon. | ||
Genes controlled by S-box element: | Genes controlled by S-box element: | ||
| − | * ''[[cysH]]'' | + | * ''[[cysH]]-[[cysP]]-[[sat]]-[[cysC]]-[[ylnD]]-[[ylnE]]-[[ylnF]]'' |
* ''[[metE]]'' | * ''[[metE]]'' | ||
* ''[[metK]]'' | * ''[[metK]]'' | ||
Revision as of 11:12, 7 June 2009
The S-box element is a riboswitch that controls different genes of sulphur metabolism in response to the presence of S-adenosylmethionine.
- Upon binding of SAM, the riboswitch adopts a terminator structure resulting in transcription termination.
- In the aabsence of SAM, the riboswitch has the antitermination structure that allows transcription elongation into the controlled gene/ operon.
Genes controlled by S-box element:
- cysH-cysP-sat-cysC-ylnD-ylnE-ylnF
- metE
- metK
- yitJ-yitI-yitH
- yjcI-yjcJ
- mtnK-mtnS
- ykrW
- yoaD
- yusC
- yxjG
- yxjH
References
Jerneja Tomsic, Brooke A McDaniel, Frank J Grundy, Tina M Henkin
Natural variability in S-adenosylmethionine (SAM)-dependent riboswitches: S-box elements in bacillus subtilis exhibit differential sensitivity to SAM In vivo and in vitro.
J Bacteriol: 2008, 190(3);823-33
[PubMed:18039762]
[WorldCat.org]
[DOI]
(I p)
T M Henkin, F J Grundy
Sensing metabolic signals with nascent RNA transcripts: the T box and S box riboswitches as paradigms.
Cold Spring Harb Symp Quant Biol: 2006, 71;231-7
[PubMed:17381302]
[WorldCat.org]
[DOI]
(P p)
