Difference between revisions of "MalS"

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=== Basic information ===
 
=== Basic information ===
  
* '''Locus tag:'''
+
* '''Locus tag:''' BSU29880
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
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* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/O34389 O34389]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/O34389 O34389]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU29880 BSU29880]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU29880]
  
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/1.1.1.38 1.1.1.38]
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/1.1.1.38 1.1.1.38]

Revision as of 09:41, 3 June 2009

  • Description: malate dehydrogenase (decarboxylating)

Gene name malS
Synonyms
Essential no
Product malate dehydrogenase (decarboxylating)
Function malate utilization
MW, pI 61 kDa, 4.895
Gene length, protein length 1698 bp, 566 aa
Immediate neighbours ytzB, ytnP
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
MalS context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU29880

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: (S)-malate + NAD+ = pyruvate + CO2 + NADH (according to Swiss-Prot) malate --> pyruvate
  • Protein family: malic enzymes family (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Doan, T., P. Servant, S. Tojo, H. Yamaguchi, G. Lerondel, K. Yoshida, Y. Fujita, and S. Aymerich. 2003. The Bacillus subtilis ywkA gene encodes a malic enzyme and its transcription is activated by the YufL/YufM two-component system in response to malate. Microbiology 149: 2331-2343. PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed