Difference between revisions of "AcuA"
| Line 20: | Line 20: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[acsA]]'', ''[[acuB]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[acsA]]'', ''[[acuB]]'' | ||
|- | |- | ||
| − | |style="background:#FAF8CC;" align="center"|'''[http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB14947]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' |
| − | |||
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:acuA_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:acuA_context.gif]] | ||
Revision as of 01:39, 17 April 2009
- Description: protein acetylase for the control of AcsA activity
| Gene name | acuA |
| Synonyms | |
| Essential | no |
| Product | Gcn5-related N-acetyltransferase |
| Function | control of AcsA activity |
| MW, pI | 24 kDa, 5.028 |
| Gene length, protein length | 630 bp, 210 aa |
| Immediate neighbours | acsA, acuB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: acetylates (and thereby inactivates) AcsA on Lys-549 PubMed PubMed
- Protein family: Gcn5-relatedN-acetyltransferase PubMed
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry:
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulatory mechanism: CcpA: transcription repression
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Blencke et al. (2003) Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways. Metab Eng. 5: 133-149 PubMed
- Gardner JG, Escalante-Semerena JC (2008) Biochemical and mutational analyses of AcuA, the acetyltransferase enzyme that controls the activity of the acetyl coenzyme a synthetase (AcsA) in Bacillus subtilis. J. Bacteriol. 190: 5132-5136. PubMed
- Gardner JG, Escalante-Semerena JC (2009) In Bacillus subtilis, the sirtuin protein deacetylase, encoded by the srtN gene (formerly yhdZ), and functions encoded by the acuABC genes control the activity of acetyl coenzyme A synthetase. J. Bacteriol. 191: 1749-1755. PubMed
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
