MleA

• Description: malic enzyme
  
  

Gene name	mleA
Synonyms	yqkJ
Essential	no
Product	NAD-dependent malate dehydrogenase
Function	malate utilization
MW, pI	45 kDa, 4.895
Gene length, protein length	1317 bp, 439 aa
Immediate neighbours	yqkK, mleN
Gene sequence (+200bp)	Protein sequence
Genetic context

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: malate --> pyruvate

• Protein family:

• Paralogous protein(s): YtsJ

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• Swiss prot entry:

• KEGG entry:

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Lerondel G, Doan T, Zamboni N, Sauer U, Aymerich S. (2006) YtsJ has the major physiological role of the four paralogous malic enzyme isoforms in Bacillus subtilis. J Bacteriol. 188 4727-4736. PubMed
2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed