Difference between revisions of "Fla-che operon"

From SubtiWiki
Jump to: navigation, search
(Created page with "The fla-che operon encodes major factors required for motility and chemotaxis * ''flgB-flgC-fliE-fliF-fliG-fliH-fliI-fliJ-ylxF-[[f...")
 
 
(5 intermediate revisions by the same user not shown)
Line 1: Line 1:
 
The [[fla-che operon]] encodes major factors required for [[motility and chemotaxis]]
 
The [[fla-che operon]] encodes major factors required for [[motility and chemotaxis]]
  
* ''[[flgB]]-[[flgC]]-[[fliE]]-[[fliF]]-[[fliG]]-[[fliH]]-[[fliI]]-[[fliJ]]-[[ylxF]]-[[fliK]]-[[flgD]]-[[flgE]]-[[fliL]]-[[fliM]]-[[fliY]]-[[cheY]]-[[fliZ]]-[[fliP]]-[[fliQ]]-[[fliR]]-[[flhB]]-[[flhA]]-[[flhF]]-[[flhG]]-[[cheB]]-[[cheA]]-[[cheW]]-[[cheC]]-[[cheD]]-[[sigD]]-[[swrB]]'' {{PubMed|9657996,8157612,15175317}}
+
* The operon is expressed from promoters upstream of ''[[flgB]]'', ''[[ylxF]]'', and ''[[sigD]]'':
 +
** ''[[flgB]]-[[flgC]]-[[fliE]]-[[fliF]]-[[fliG]]-[[fliH]]-[[fliI]]-[[fliJ]]-[[ylxF]]-[[fliK]]-[[flgD]]-[[flgE]]-[[fliL]]-[[fliM]]-[[fliY]]-[[cheY]]-[[fliZ]]-[[fliP]]-[[fliQ]]-[[fliR]]-[[flhB]]-[[flhA]]-[[flhF]]-[[flhG]]-[[cheB]]-[[cheA]]-[[cheW]]-[[cheC]]-[[cheD]]-[[sigD]]-[[swrB]]'' {{PubMed|9657996,8157612,15175317}}
 +
** ''[[ylxF]]-[[fliK]]-[[flgD]]-[[flgE]]-[[fliL]]-[[fliM]]-[[fliY]]-[[cheY]]-[[fliZ]]-[[fliP]]-[[fliQ]]-[[fliR]]-[[flhB]]-[[flhA]]-[[flhF]]-[[flhG]]-[[cheB]]-[[cheA]]-[[cheW]]-[[cheC]]-[[cheD]]-[[sigD]]-[[swrB]]'' {{PubMed|20233303}}
 +
** ''[[sigD]]-[[swrB]]'' {{PubMed|9335309}}
 +
 
 +
* '''[[Sigma factor]]:'''
 +
** ''[[flgB]]'': [[SigA]] {{PubMed|9657996}}, [[SigD]] {{PubMed|9657996}}
 +
** ''[[ylxF]]'': [[SigD]] {{PubMed|20233303}}
 +
** ''[[sigD]]'': [[SigA]] {{PubMed|9335309}}
 +
 
 +
* '''Regulation:'''
 +
** repressed under conditions that trigger sporulation ([[Spo0A]]) {{PubMed|14651647}}
 +
** reduced expression in the absence of [[PnpA]] (due to accumulation of [[SlrA]]) {{PubMed|26857544}}
 +
 
 +
* '''Regulatory mechanism:'''
 +
** [[Spo0A]]: transcription repression {{PubMed|14651647}}
 +
** [[CodY]]: transcription repression {{PubMed|12730172}}
 +
** [[DegU]] (non-phosphorylated): transcription activation {{PubMed|17850253}}
 +
** [[DegU]]-P: transcription repression {{PubMed|24386445}}
 +
** [[DegU]]-P in complex with [[SwrA]]: transcription activation {{PubMed|24386445}}
 +
 
 +
=== Important publications on the expression and regulation of the ''fla-che'' operon ===
 +
<pubmed> 26170408, 26857544 </pubmed>
 +
== Back to [[operons]] ==

Latest revision as of 14:43, 8 October 2017

The fla-che operon encodes major factors required for motility and chemotaxis

  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
    • reduced expression in the absence of PnpA (due to accumulation of SlrA) PubMed

Important publications on the expression and regulation of the fla-che operon

Back to operons