Difference between revisions of "Fla-che operon"
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The [[fla-che operon]] encodes major factors required for [[motility and chemotaxis]] | The [[fla-che operon]] encodes major factors required for [[motility and chemotaxis]] | ||
− | * ''[[flgB]]-[[flgC]]-[[fliE]]-[[fliF]]-[[fliG]]-[[fliH]]-[[fliI]]-[[fliJ]]-[[ylxF]]-[[fliK]]-[[flgD]]-[[flgE]]-[[fliL]]-[[fliM]]-[[fliY]]-[[cheY]]-[[fliZ]]-[[fliP]]-[[fliQ]]-[[fliR]]-[[flhB]]-[[flhA]]-[[flhF]]-[[flhG]]-[[cheB]]-[[cheA]]-[[cheW]]-[[cheC]]-[[cheD]]-[[sigD]]-[[swrB]]'' {{PubMed|9657996,8157612,15175317}} | + | * The operon is expressed from promoters upstream of ''[[flgB]]'', ''[[ylxF]]'', and ''[[sigD]]'': |
+ | ** ''[[flgB]]-[[flgC]]-[[fliE]]-[[fliF]]-[[fliG]]-[[fliH]]-[[fliI]]-[[fliJ]]-[[ylxF]]-[[fliK]]-[[flgD]]-[[flgE]]-[[fliL]]-[[fliM]]-[[fliY]]-[[cheY]]-[[fliZ]]-[[fliP]]-[[fliQ]]-[[fliR]]-[[flhB]]-[[flhA]]-[[flhF]]-[[flhG]]-[[cheB]]-[[cheA]]-[[cheW]]-[[cheC]]-[[cheD]]-[[sigD]]-[[swrB]]'' {{PubMed|9657996,8157612,15175317}} | ||
+ | ** ''[[ylxF]]-[[fliK]]-[[flgD]]-[[flgE]]-[[fliL]]-[[fliM]]-[[fliY]]-[[cheY]]-[[fliZ]]-[[fliP]]-[[fliQ]]-[[fliR]]-[[flhB]]-[[flhA]]-[[flhF]]-[[flhG]]-[[cheB]]-[[cheA]]-[[cheW]]-[[cheC]]-[[cheD]]-[[sigD]]-[[swrB]]'' {{PubMed|20233303}} | ||
+ | ** ''[[sigD]]-[[swrB]]'' {{PubMed|9335309}} | ||
+ | |||
+ | * '''[[Sigma factor]]:''' | ||
+ | ** ''[[flgB]]'': [[SigA]] {{PubMed|9657996}}, [[SigD]] {{PubMed|9657996}} | ||
+ | ** ''[[ylxF]]'': [[SigD]] {{PubMed|20233303}} | ||
+ | ** ''[[sigD]]'': [[SigA]] {{PubMed|9335309}} | ||
+ | |||
+ | * '''Regulation:''' | ||
+ | ** repressed under conditions that trigger sporulation ([[Spo0A]]) {{PubMed|14651647}} | ||
+ | ** reduced expression in the absence of [[PnpA]] (due to accumulation of [[SlrA]]) {{PubMed|26857544}} | ||
+ | |||
+ | * '''Regulatory mechanism:''' | ||
+ | ** [[Spo0A]]: transcription repression {{PubMed|14651647}} | ||
+ | ** [[CodY]]: transcription repression {{PubMed|12730172}} | ||
+ | ** [[DegU]] (non-phosphorylated): transcription activation {{PubMed|17850253}} | ||
+ | ** [[DegU]]-P: transcription repression {{PubMed|24386445}} | ||
+ | ** [[DegU]]-P in complex with [[SwrA]]: transcription activation {{PubMed|24386445}} | ||
+ | |||
+ | === Important publications on the expression and regulation of the ''fla-che'' operon === | ||
+ | <pubmed> 26170408, 26857544 </pubmed> | ||
+ | == Back to [[operons]] == |
Latest revision as of 14:43, 8 October 2017
The fla-che operon encodes major factors required for motility and chemotaxis
- The operon is expressed from promoters upstream of flgB, ylxF, and sigD:
- flgB-flgC-fliE-fliF-fliG-fliH-fliI-fliJ-ylxF-fliK-flgD-flgE-fliL-fliM-fliY-cheY-fliZ-fliP-fliQ-fliR-flhB-flhA-flhF-flhG-cheB-cheA-cheW-cheC-cheD-sigD-swrB PubMed
- ylxF-fliK-flgD-flgE-fliL-fliM-fliY-cheY-fliZ-fliP-fliQ-fliR-flhB-flhA-flhF-flhG-cheB-cheA-cheW-cheC-cheD-sigD-swrB PubMed
- sigD-swrB PubMed
- Regulation:
- Regulatory mechanism:
Important publications on the expression and regulation of the fla-che operon