YmfD

• Description: exporter for the siderophore bacillibactin
  
  

Gene name	ymfD
Synonyms
Essential	no
Product	bacillibactin exporter
Function	iron acquisition
Gene expression levels in SubtiExpress: ymfD
MW, pI	44 kDa, 8.355
Gene length, protein length	1206 bp, 402 aa
Immediate neighbours	ymfC, ymfF
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, acquisition of iron, iron metabolism, membrane proteins, sporulation/ other

This gene is a member of the following regulons

Mta regulon

The gene

Basic information

• Locus tag: BSU16825

Database entries

• BsubCyc: BSU16825

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: major facilitator superfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• BsubCyc: BSU16825

• Structure:

• Swiss prot entry: O31762

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: ymfD-ymfF-ymfH PubMed

• Expression browser: ymfD PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:
  • Mta: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Marcus Miethke, Sarah Schmidt, Mohamed A Marahiel
The major facilitator superfamily-type transporter YmfE and the multidrug-efflux activator Mta mediate bacillibactin secretion in Bacillus subtilis.
J Bacteriol: 2008, 190(15);5143-52
[PubMed:18502870] [WorldCat.org] [DOI] (I p)