Difference between revisions of "FlgK"

From SubtiWiki
Jump to: navigation, search
Line 20: Line 20:
 
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1521 bp, 507 aa  
 
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1521 bp, 507 aa  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[flgL]]'', ''[[yvyG]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[flgL]]'', ''[[flgN]]''
 
|-
 
|-
 
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU35410 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU35410 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU35410 DNA_with_flanks]
 
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU35410 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU35410 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU35410 DNA_with_flanks]
Line 35: Line 35:
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
 
 
 
<br/><br/>
 
<br/><br/>
  
Line 65: Line 61:
  
 
=== Additional information===
 
=== Additional information===
 
 
 
  
 
=The protein=
 
=The protein=
Line 83: Line 76:
 
* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
+
* '''[[Domains]]:'''  
  
 
* '''Modification:'''
 
* '''Modification:'''
  
* '''Cofactor(s):'''
+
* '''[[Cofactors]]:'''
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
Line 111: Line 104:
 
=Expression and regulation=
 
=Expression and regulation=
 
* '''Operon:'''  
 
* '''Operon:'''  
** ''[[comFA]]-[[comFB]]-[[comFC]]-[[yvyF]]-[[flgM]]-[[yvyG]]-[[flgK]]-[[flgL]]'' {{PubMed|8412657}}
+
** ''[[comFA]]-[[comFB]]-[[comFC]]-[[yvyF]]-[[flgM]]-[[flgN]]-[[flgK]]-[[flgL]]'' {{PubMed|8412657}}
** ''[[yvyF]]-[[flgM]]-[[yvyG]]-[[flgK]]-[[flgL]]'' {{PubMed|8045879}}
+
** ''[[yvyF]]-[[flgM]]-[[flgN]]-[[flgK]]-[[flgL]]'' {{PubMed|8045879}}
** ''[[flgM]]-[[yvyG]]-[[flgK]]-[[flgL]]'' {{PubMed|21736639}}
+
** ''[[flgM]]-[[flgN]]-[[flgK]]-[[flgL]]'' {{PubMed|21736639}}
  
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=flgK_3638245_3639768_-1 flgK] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=flgK_3638245_3639768_-1 flgK] {{PubMed|22383849}}
  
* '''Sigma factor:'''  
+
* '''[[Sigma factor]]:'''  
 
** ''[[comFA]]'': [[SigA]] {{PubMed|8412657}}
 
** ''[[comFA]]'': [[SigA]] {{PubMed|8412657}}
 
** ''[[yvyF]]'': [[SigD]] {{PubMed|8045879}}
 
** ''[[yvyF]]'': [[SigD]] {{PubMed|8045879}}
Line 149: Line 142:
  
 
=References=
 
=References=
'''Additional publications:''' {{PubMed|21736639}}
+
<pubmed>8412657 8045879 18957862, 21736639</pubmed>
<pubmed>8412657 8045879 18957862, </pubmed>
 
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 14:44, 8 April 2014

  • Description: flagellar hook-associated protein 1 (HAP1)

Gene name flgK
Synonyms
Essential no
Product flagellar hook-associated protein 1 (HAP1)
Function movement and chemotaxis
Gene expression levels in SubtiExpress: flgK
MW, pI 54 kDa, 4.375
Gene length, protein length 1521 bp, 507 aa
Immediate neighbours flgL, flgN
Sequences Protein DNA DNA_with_flanks
Genetic context
FlgK context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FlgK expression.png















Categories containing this gene/protein

motility and chemotaxis

This gene is a member of the following regulons

ComK regulon, DegU regulon, SigD regulon

The gene

Basic information

  • Locus tag: BSU35410

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: flagella basal body rod proteins family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Yi-Huang Hsueh, Loralyn M Cozy, Lok-To Sham, Rebecca A Calvo, Alina D Gutu, Malcolm E Winkler, Daniel B Kearns
DegU-phosphate activates expression of the anti-sigma factor FlgM in Bacillus subtilis.
Mol Microbiol: 2011, 81(4);1092-108
[PubMed:21736639] [WorldCat.org] [DOI] (I p)

Birgit Voigt, Haike Antelmann, Dirk Albrecht, Armin Ehrenreich, Karl-Heinz Maurer, Stefan Evers, Gerhard Gottschalk, Jan Maarten van Dijl, Thomas Schweder, Michael Hecker
Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis.
J Mol Microbiol Biotechnol: 2009, 16(1-2);53-68
[PubMed:18957862] [WorldCat.org] [DOI] (I p)

D B Mirel, P Lauer, M J Chamberlin
Identification of flagellar synthesis regulatory and structural genes in a sigma D-dependent operon of Bacillus subtilis.
J Bacteriol: 1994, 176(15);4492-500
[PubMed:8045879] [WorldCat.org] [DOI] (P p)

J A Londoño-Vallejo, D Dubnau
comF, a Bacillus subtilis late competence locus, encodes a protein similar to ATP-dependent RNA/DNA helicases.
Mol Microbiol: 1993, 9(1);119-31
[PubMed:8412657] [WorldCat.org] [DOI] (P p)