Difference between revisions of "SpsK"

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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU37820&redirect=T BSU37820]
  
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/sps.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/sps.html]
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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU37820&redirect=T BSU37820]
  
 
* '''Structure:''' [http://www.pdb.org/pdb/explore/explore.do?structureId=3SC6 3SC6] (dTDP-4-dehydrorhamnose reductase (''rfbD'') from ''Bacillus anthracis'' str. Ames in complex with NADP; 42% identity, 72% similarity)
 
* '''Structure:''' [http://www.pdb.org/pdb/explore/explore.do?structureId=3SC6 3SC6] (dTDP-4-dehydrorhamnose reductase (''rfbD'') from ''Bacillus anthracis'' str. Ames in complex with NADP; 42% identity, 72% similarity)

Revision as of 15:06, 2 April 2014

  • Description: dTDP -4-dehydrorhamnose reductase, spore coat polysaccharide synthesis

Gene name spsK
Synonyms ipa-73d
Essential no
Product dTDP -4-dehydrorhamnose reductase
Function rhamnose biosynthesis, spore coat polysaccharide synthesis
Gene expression levels in SubtiExpress: spsK
MW, pI 31 kDa, 6.081
Gene length, protein length 849 bp, 283 aa
Immediate neighbours spsL, spsJ
Sequences Protein DNA DNA_with_flanks
Genetic context
SpsK context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SpsK expression.png















Categories containing this gene/protein

miscellaneous metabolic pathways, sporulation proteins

This gene is a member of the following regulons

SigE regulon, SigK regulon

The gene

Basic information

  • Locus tag: BSU37820

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: dTDP-4-dehydrorhamnose reductase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 3SC6 (dTDP-4-dehydrorhamnose reductase (rfbD) from Bacillus anthracis str. Ames in complex with NADP; 42% identity, 72% similarity)
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • expressed late during sporulation in the mother cell (SigK) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References