Difference between revisions of "GerD"

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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU01550&redirect=T BSU01550]
  
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/gerD.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/gerD.html]
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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU01550&redirect=T BSU01550]
  
 
* '''Structure:''' [http://pdb.org/pdb/explore/explore.do?structureId=4O8W 4O8W] {{PubMed|24530795}}
 
* '''Structure:''' [http://pdb.org/pdb/explore/explore.do?structureId=4O8W 4O8W] {{PubMed|24530795}}

Revision as of 12:51, 2 April 2014

  • Description: scaffold of the germinosome, required for clustering of germinant receptors in the spore inner membrane

Gene name gerD
Synonyms
Essential no
Product lipoprotein
Function germination
Gene expression levels in SubtiExpress: gerD
Interactions involving this protein in SubtInteract: GerD
MW, pI 20 kDa, 4.862
Gene length, protein length 555 bp, 185 aa
Immediate neighbours salA, kbaA
Sequences Protein DNA DNA_with_flanks
Genetic context
GerD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
GerD expression.png















Categories containing this gene/protein

germination, membrane proteins

This gene is a member of the following regulons

SigF regulon, SigG regulon

The gene

Basic information

  • Locus tag: BSU01550

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: required for clustering of germinant receptors in the spore inner membrane PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
    • has an N-terminal signal sequence and a signal for fixation to lipid PubMed
  • Modification:
  • Effectors of protein activity:
  • Localization:
    • outer surface of the inner spore membrane PubMed
    • inner spore membrane, spore coat, cortex, germ cell wall, some GerD is also present in the soluble fraction PubMed

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

  • 3,500 molecules are present per spore PubMed

Expression and regulation

  • Regulation:
    • expression level depends on sporulation conditions (medim composition, temperature) PubMed
  • Regulatory mechanism:
  • Additional information:
    • 3,500 molecules are present per spore PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:

Labs working on this gene/protein

Anne Moir, University of Sheffield, UK

Your additional remarks

References