Difference between revisions of "Transport proteins"

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(→‎Ion export)
 
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* Channel of large conductance: [[MscL]]
 
* Channel of large conductance: [[MscL]]
 
* Channels of small conductance: [[YfkC]], [[YhdY]], [[YkuT]]
 
* Channels of small conductance: [[YfkC]], [[YhdY]], [[YkuT]]
 +
* Channel implicated in [[sporulation]]: [[SpoVAC]]
 +
** a mutant devoid of all four mechanosensitive channels (TMB99, Δ(''[[mscL]]''::''spc'') Δ(''[[ykuT]]''::''cat'')  Δ(''[[yhdY]]''::''ery'') Δ(''[[yfkC]]''::''kan'')) is available in [[Erhard Bremer]]'s lab {{PubMed|22685134}}
  
 
=Ion transporters=
 
=Ion transporters=
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* monovalent cation (Na, K, Li, Rb)/H(+) antiporter: [[NhaK]]
 
* monovalent cation (Na, K, Li, Rb)/H(+) antiporter: [[NhaK]]
  
−
=Amino acid transporter=
+
= ECF transporter for the uptake of micronutrients =
−
* glutamate: [[GltP]], [[GltP]]
+
* ([[YbxA]]-[[YbaE]])-[[YbaF]] (general components)
−
* proline: [[YcgO]]
+
* [[RibU]]
 +
* [[ThiT]]
 +
* [[YhfU]]
 +
* [[TrpP]]
 +
 
 +
=Amino acid uptake=
 +
* arginine: [[ArtP]]-[[ArtQ]]-[[ArtR]]
 +
* branched-chain amino acids: [[BraB]], [[BrnQ]]
 +
* cystine: [[TcyA]]-[[TcyB]]-[[TcyC]]; [[TcyJ]]-[[TcyK]]-[[TcyL]]-[[TcyM]]-[[TcyN]]
 +
* glutamate: [[GltP]]; [[GltP]]
 +
* glutamine: [[GlnH]]-[[GlnM]]-[[GlnP]]-[[GlnQ]]
 +
* lysine: [[YvsH]]
 +
* methionine: [[MetN]]-[[MetP]]-[[MetQ]]
 +
* proline: [[PutP]]
 +
* tryptophan: ([[YbxA]]-[[YbaE]])-[[YbaF]]-[[TrpP]]
 +
 
 +
=Nucleotide and nucleoside transporters=
 +
==Nucleotide and nucleoside uptake==
 +
* hypoxanthine/ guanine: [[PbuG]]
 +
* hypoxanthine/ guanine: [[PbuO]] (based on similarity)
 +
 
 +
==Nucleotide and nucleoside export==
 +
* hypoxanthine: [[PbuE]] (putative)
  
 
=Sugar transport proteins=
 
=Sugar transport proteins=
 +
==ABC transporters==
 +
* ATP-binding subunit for multiple [[ABC transporter]]s: [[MsmX]]
 +
* aminosugar uptake: [[YurJ]]-[[YurM]]-[[YurN]]-[[YurO]]
 +
* arabinose uptake: [[AraN]]-[[AraP]]-[[AraQ]]
 +
* galactotriose uptake: [[CycB]]-[[GanP]]-[[GanQ]]
 +
* maltodextrin uptake: [[MdxE]]-[[MdxF]]-[[MdxG]]
 +
* melibiose uptake: [[AmyC]]-[[AmyD]]-[[MsmE]]
 +
* ribose uptake: [[RbsA]]-[[RbsB]]-[[RbsC]]-[[RbsD]]
 +
 
==[[PTS]] proteins==
 
==[[PTS]] proteins==
 
* General [[PTS]] proteins: [[ptsI|Enzyme I]], [[ptsH|HPr]]
 
* General [[PTS]] proteins: [[ptsI|Enzyme I]], [[ptsH|HPr]]
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* [[GamP]]: glucosamine permease, EIICBA
 
* [[GamP]]: glucosamine permease, EIICBA
 
* [[MurP]]: N-acetyl muramic acid-specific phosphotransferase system, EIIBC component  
 
* [[MurP]]: N-acetyl muramic acid-specific phosphotransferase system, EIIBC component  
−
* [[MtlA]]: mannitol permease
+
* [[MtlA]], [[MtlF]]: mannitol permease
 
* [[GmuA]], [[GmuB]], [[GmuC]]: galactomannan permease
 
* [[GmuA]], [[GmuB]], [[GmuC]]: galactomannan permease
 
* [[TreP]]: trehalose permease
 
* [[TreP]]: trehalose permease
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* [[BglP]]: ß-glucoside permease
 
* [[BglP]]: ß-glucoside permease
 
* [[YyzE]]: unknown PTS protein
 
* [[YyzE]]: unknown PTS protein
−
* [[MtlF]]
 
 
* [[YwbA]]: unknown EIIC component
 
* [[YwbA]]: unknown EIIC component
  
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* [http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]
 
* [http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]
 
* [http://subtiwiki.uni-goettingen.de/pathways/carbohydrate_metabolic_pathways.html Sugar catabolism]
 
* [http://subtiwiki.uni-goettingen.de/pathways/carbohydrate_metabolic_pathways.html Sugar catabolism]
 +
 +
=Transporters for the uptake of compatible solutes in response to hyperosmolarity=
 +
* [[OpuAA]]-[[OpuAB]]-[[OpuAC]]: [[ABC transporter]] for glycine betaine
 +
* [[OpuBA]]-[[OpuBB]]-[[OpuBC]]-[[OpuBD]]: [[ABC transporter]] for choline
 +
* [[OpuCA]]-[[OpuCB]]-[[OpuCC]]-[[OpuCD]]: [[ABC transporter]] for glycine betaine/ carnitine/ choline
 +
* [[OpuD]]: transporter for glycine betaine
 +
* [[OpuE]]: transporter for proline
 +
 +
==Uptake of siderophores==
 +
* petrobactin: [[YclN]]-[[YclO]]-[[YclP]]-[[YclQ]]
 +
  
 
=Related Lists=
 
=Related Lists=
−
* [[PTS]]
+
* [[ABC transporter]], [[PTS]]
 +
 
 +
=External Links=
 +
[http://www.tcdb.org/ The Transporter Classification Database]
  
−
==Relevant Reviews==
+
=Relevant Reviews=
−
<pubmed>17158705 9871918 9663674 10627040  </pubmed>
+
<pubmed>10627040 10092453 12626684 11763970 10627041 20825352 22685280 20497229 24258154 </pubmed>

Latest revision as of 17:51, 31 March 2014

Mechanosensitive channels

Ion transporters

Ion uptake

Ion export

ECF transporter for the uptake of micronutrients

Amino acid uptake

Nucleotide and nucleoside transporters

Nucleotide and nucleoside uptake

  • hypoxanthine/ guanine: PbuG
  • hypoxanthine/ guanine: PbuO (based on similarity)

Nucleotide and nucleoside export

  • hypoxanthine: PbuE (putative)

Sugar transport proteins

ABC transporters

PTS proteins

  • General PTS proteins: Enzyme I, HPr
  • PtsG: glucose permease, EIICBA
  • GamP: glucosamine permease, EIICBA
  • MurP: N-acetyl muramic acid-specific phosphotransferase system, EIIBC component
  • MtlA, MtlF: mannitol permease
  • GmuA, GmuB, GmuC: galactomannan permease
  • TreP: trehalose permease
  • MalP: maltose permease
  • FruA: fructose permease
  • ManP: mannose permease
  • YpqE: unknown EIIA component
  • LevD, LevE, LevF, LevG: fructose permease
  • SacP: sucrose permease (high affinity)
  • SacY: sucrose permease (low affinity)
  • LicA, LicB, LicC: lichenan permease
  • BglP: ß-glucoside permease
  • YyzE: unknown PTS protein
  • YwbA: unknown EIIC component

The PTS in SubtiPathways

Transporters for the uptake of compatible solutes in response to hyperosmolarity

Uptake of siderophores


Related Lists

External Links

The Transporter Classification Database

Relevant Reviews

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