Difference between revisions of "GntZ"
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=== Additional information=== | === Additional information=== | ||
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=The protein= | =The protein= | ||
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* '''Protein family:''' 6-phosphogluconate dehydrogenase family (according to Swiss-Prot) | * '''Protein family:''' 6-phosphogluconate dehydrogenase family (according to Swiss-Prot) | ||
| − | * '''Paralogous protein(s):''' | + | * '''Paralogous protein(s):''' [[GndA]] |
=== Extended information on the protein === | === Extended information on the protein === | ||
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' | + | * '''[[Domains]]:''' |
* '''Modification:''' | * '''Modification:''' | ||
| − | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
Revision as of 13:17, 28 March 2014
- Description: 6-phosphogluconate dehydrogenase
| Gene name | gntZ |
| Synonyms | |
| Essential | no |
| Product | 6-phosphogluconate dehydrogenase |
| Function | gluconate utilization |
| Gene expression levels in SubtiExpress: gntZ | |
| Metabolic function and regulation of this protein in SubtiPathways: gntZ | |
| MW, pI | 51 kDa, 4.756 |
| Gene length, protein length | 1404 bp, 468 aa |
| Immediate neighbours | gntP, ahpC |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
utilization of specific carbon sources
This gene is a member of the following regulons
AbrB regulon, CcpA regulon, GntR regulon
The gene
Basic information
- Locus tag: BSU40080
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH (according to Swiss-Prot)
- Protein family: 6-phosphogluconate dehydrogenase family (according to Swiss-Prot)
- Paralogous protein(s): GndA
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P12013
- KEGG entry: [3]
- E.C. number: 1.1.1.44
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Ken-Ichi Yoshida, Izumi Ishio, Eishi Nagakawa, Yoshiyuki Yamamoto, Mami Yamamoto, Yasutaro Fujita
Systematic study of gene expression and transcription organization in the gntZ-ywaA region of the Bacillus subtilis genome.
Microbiology (Reading): 2000, 146 ( Pt 3);573-579
[PubMed:10746760]
[WorldCat.org]
[DOI]
(P p)
Y Fujita, Y Miwa
Catabolite repression of the Bacillus subtilis gnt operon mediated by the CcpA protein.
J Bacteriol: 1994, 176(2);511-3
[PubMed:8288545]
[WorldCat.org]
[DOI]
(P p)
Y Miwa, Y Fujita
Promoter-independent catabolite repression of the Bacillus subtilis gnt operon.
J Biochem: 1993, 113(6);665-71
[PubMed:8370661]
[WorldCat.org]
[DOI]
(P p)
A Reizer, J Deutscher, M H Saier, J Reizer
Analysis of the gluconate (gnt) operon of Bacillus subtilis.
Mol Microbiol: 1991, 5(5);1081-9
[PubMed:1659648]
[WorldCat.org]
[DOI]
(P p)
Y Fujita, T Fujita
The gluconate operon gnt of Bacillus subtilis encodes its own transcriptional negative regulator.
Proc Natl Acad Sci U S A: 1987, 84(13);4524-8
[PubMed:3037520]
[WorldCat.org]
[DOI]
(P p)
Y Fujita, T Fujita, Y Miwa, J Nihashi, Y Aratani
Organization and transcription of the gluconate operon, gnt, of Bacillus subtilis.
J Biol Chem: 1986, 261(29);13744-53
[PubMed:3020045]
[WorldCat.org]
(P p)
Y Fujita, J Nihashi, T Fujita
The characterization and cloning of a gluconate (gnt) operon of Bacillus subtilis.
J Gen Microbiol: 1986, 132(1);161-9
[PubMed:3011959]
[WorldCat.org]
[DOI]
(P p)
