Difference between revisions of "MntA"

From SubtiWiki
Jump to: navigation, search
Line 8: Line 8:
 
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ytgA ''
 
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ytgA ''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/17114254 PubMed]
+
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Product''' || manganese [[ABC transporter]] (binding protein)
 
|style="background:#ABCDEF;" align="center"| '''Product''' || manganese [[ABC transporter]] (binding protein)
Line 43: Line 43:
 
= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
 
{{SubtiWiki category|[[ABC transporters]]}},
 
{{SubtiWiki category|[[ABC transporters]]}},
{{SubtiWiki category|[[trace metal homeostasis (Cu, Zn, Ni, Mn, Mo)]]}},
+
{{SubtiWiki category|[[trace metal homeostasis (Cu, Zn, Ni, Mn, Mo)]]}}
{{SubtiWiki category|[[essential genes]]}}
 
  
 
= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
Line 56: Line 55:
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 
+
* essential according to [http://www.ncbi.nlm.nih.gov/pubmed/17114254 Kobayashi et al.], but a mutant has been constructed and studied by [http://www.ncbi.nlm.nih.gov/pubmed/10760146 Que amd Helmann, 2000]
essential [http://www.ncbi.nlm.nih.gov/pubmed/17114254 PubMed]
 
  
 
=== Database entries ===
 
=== Database entries ===

Revision as of 15:17, 10 February 2014

Gene name mntA
Synonyms ytgA
Essential no
Product manganese ABC transporter (binding protein)
Function manganese uptake
Gene expression levels in SubtiExpress: mntA
Interactions involving this protein in SubtInteract: MntA
Metabolic function and regulation of this protein in SubtiPathways:
mntA
MW, pI 33 kDa, 6.162
Gene length, protein length 918 bp, 306 aa
Immediate neighbours mntB, menC
Sequences Protein DNA DNA_with_flanks
Genetic context
MntA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MntA expression.png















Categories containing this gene/protein

ABC transporters, trace metal homeostasis (Cu, Zn, Ni, Mn, Mo)

This gene is a member of the following regulons

MntR regulon

The gene

Basic information

  • Locus tag: BSU30770

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: bacterial solute-binding protein 9 family (according to Swiss-Prot)
  • Paralogous protein(s): ZnuA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cell membrane (according to Swiss-Prot), extracellular lipoprotein (signal peptide) PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • repressed at high Mn(II) concentrations (MntR) PubMed
  • Regulatory mechanism:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

John Helmann, Cornell University, USA Homepage

Your additional remarks

References