Difference between revisions of "HtrC"
Line 1: | Line 1: | ||
− | * '''Description:''' similar to serine protease HtrA <br/><br/> | + | * '''Description:''' similar to quality control membrane serine protease [[HtrA]] <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Gene name''' | |style="background:#ABCDEF;" align="center"|'''Gene name''' | ||
− | |'' | + | |''htrC'' |
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yycK '' | + | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yycK, yyxA '' |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || putative quality control membrane protease |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown | |style="background:#ABCDEF;" align="center"|'''Function''' || unknown | ||
|- | |- | ||
− | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU40360 | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU40360 htrC] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 5.315 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 5.315 | ||
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
− | * '''Domains:''' | + | * '''[[Domains]]:''' |
* '''Modification:''' | * '''Modification:''' | ||
− | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
− | ** [[ | + | ** [[HtrC]] is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of [[SubtInteract|interactions]] {{PubMed|21630458}} |
* '''[[Localization]]:''' cell membrane (according to Swiss-Prot) | * '''[[Localization]]:''' cell membrane (according to Swiss-Prot) | ||
Line 102: | Line 102: | ||
=Expression and regulation= | =Expression and regulation= | ||
− | * '''Operon:''' ''[[walR]]-[[walK]]-[[yycH]]-[[yycI]]-[[walJ]]-[[ | + | * '''Operon:''' ''[[walR]]-[[walK]]-[[yycH]]-[[yycI]]-[[walJ]]-[[htrC]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed] |
''[[yyxA]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed] | ''[[yyxA]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed] | ||
− | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=htrC_4147567_4148769_-1 | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=htrC_4147567_4148769_-1 htrC] {{PubMed|22383849}} |
− | * '''Sigma factor:''' for ''[[ | + | * '''[[Sigma factor]]:''' for ''[[htrC]]'': [[SigG]] [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed] |
− | * '''Regulation:''' expressed during vegetative growth, repressed during stationary phase [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed] | + | * '''Regulation:''' |
− | + | ** expressed during vegetative growth, repressed during stationary phase [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed] | |
− | '' | + | ** ''htrC'' transcript expressed during sporulation [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed] |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
Line 140: | Line 140: | ||
<pubmed>21326199 </pubmed> | <pubmed>21326199 </pubmed> | ||
== Original publications == | == Original publications == | ||
− | <pubmed>17600057,12270824 ,11555295,18957862, 10692364 21624103 22307758 22092710 | + | <pubmed>17600057,12270824 ,11555295,18957862, 10692364 21624103 22307758 22092710 24362423 9829949,21630458 </pubmed> |
− | + | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 17:09, 15 January 2014
- Description: similar to quality control membrane serine protease HtrA
Gene name | htrC |
Synonyms | yycK, yyxA |
Essential | no |
Product | putative quality control membrane protease |
Function | unknown |
Gene expression levels in SubtiExpress: htrC | |
MW, pI | 42 kDa, 5.315 |
Gene length, protein length | 1200 bp, 400 aa |
Immediate neighbours | yyzO, walJ |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
proteolysis, sporulation proteins, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU40360
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: peptidase S1B family (according to Swiss-Prot)
- Paralogous protein(s): HtrA
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
- Interactions:
- HtrC is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of interactions PubMed
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P39668
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor: for htrC: SigG PubMed
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original publications