Difference between revisions of "GbsA"

From SubtiWiki
Jump to: navigation, search
(References)
Line 16: Line 16:
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU31060 gbsA]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU31060 gbsA]
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress]'''
+
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=gbsA gbsA]'''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 53 kDa, 4.713   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 53 kDa, 4.713   

Revision as of 11:32, 7 January 2014

  • Description: glycine betaine-aldehyde dehydrogenase, glycine betaine synthesis

Gene name gbsA
Synonyms
Essential no
Product glycine betaine-aldehyde dehydrogenase
Function osmoprotection
Gene expression levels in SubtiExpress: gbsA
Metabolic function and regulation of this protein in SubtiPathways:
gbsA
MW, pI 53 kDa, 4.713
Gene length, protein length 1470 bp, 490 aa
Immediate neighbours gbsB, gbsR
Sequences Protein DNA DNA_with_flanks
Genetic context
GbsA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
GbsA expression.png















Categories containing this gene/protein

miscellaneous metabolic pathways, coping with hyper-osmotic stress

This gene is a member of the following regulons

GbsR regulon

The gene

Basic information

  • Locus tag: BSU31060

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Betaine aldehyde + NAD+ + H2O = betaine + NADH (according to Swiss-Prot)
  • Protein family: aldehyde dehydrogenase family (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 3RHH (from from Bacillus halodurans C-125 complexed with NADP, 31% identity, 67% similarity)
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References