Difference between revisions of "GerKB"

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* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
  
* '''Protein family:''' View classification (according to Swiss-Prot)
+
** amino acid, polyamine, organocation (APC) family of transporters, [http://www.tcdb.org/search/result.php?tc=2.A.3 TC 2.A.3]
  
* '''Paralogous protein(s):'''
+
* '''Paralogous protein(s):''' [[GerAB]], [[GerBB]], [[YndE]]
  
 
=== Extended information on the protein ===
 
=== Extended information on the protein ===
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* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU03720]
 
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU03720]
  
* '''E.C. number:'''
+
* '''[http://www.tcdb.org/ T.C.] number:''' [http://www.tcdb.org/search/result.php?tc=2.A.3.9.3 2.A.3.9.3]
  
 
=== Additional information===
 
=== Additional information===

Revision as of 13:21, 28 November 2013

  • Description: nutrient receptor

Gene name gerKB
Synonyms
Essential no
Product nutrient receptor
Function germination
Gene expression levels in SubtiExpress: gerKB
Interactions involving this protein in SubtInteract: GerKB
MW, pI 41 kDa, 8.921
Gene length, protein length 1119 bp, 373 aa
Immediate neighbours gerKC, yclH
Sequences Protein DNA DNA_with_flanks
Genetic context
GerKB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
GerKB expression.png















Categories containing this gene/protein

germination, membrane proteins

This gene is a member of the following regulons

SigG regulon, SpoVT regulon

The gene

Basic information

  • Locus tag: BSU03720

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • amino acid, polyamine, organocation (APC) family of transporters, TC 2.A.3

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Jing-qiao Zhang, Keren K Griffiths, Ann Cowan, Peter Setlow, Ji Yu
Expression level of Bacillus subtilis germinant receptors determines the average rate but not the heterogeneity of spore germination.
J Bacteriol: 2013, 195(8);1735-40
[PubMed:23396907] [WorldCat.org] [DOI] (I p)

Keren K Griffiths, Jingqiao Zhang, Ann E Cowan, Ji Yu, Peter Setlow
Germination proteins in the inner membrane of dormant Bacillus subtilis spores colocalize in a discrete cluster.
Mol Microbiol: 2011, 81(4);1061-77
[PubMed:21696470] [WorldCat.org] [DOI] (I p)

Takao Igarashi, Peter Setlow
Transcription of the Bacillus subtilis gerK operon, which encodes a spore germinant receptor, and comparison with that of operons encoding other germinant receptors.
J Bacteriol: 2006, 188(11);4131-6
[PubMed:16707705] [WorldCat.org] [DOI] (P p)

Swaroopa Atluri, Katerina Ragkousi, Donna E Cortezzo, Peter Setlow
Cooperativity between different nutrient receptors in germination of spores of Bacillus subtilis and reduction of this cooperativity by alterations in the GerB receptor.
J Bacteriol: 2006, 188(1);28-36
[PubMed:16352818] [WorldCat.org] [DOI] (P p)