SdpI

• Description: immunity protein, protection against SdpC
  
  

Gene name	sdpI
Synonyms	yvaZ
Essential	no
Product	immunity protein
Function	protection against SdpC
Gene expression levels in SubtiExpress: sdpI
Interactions involving this protein in SubtInteract: SdpI
MW, pI	23 kDa, 9.61
Gene length, protein length	621 bp, 207 aa
Immediate neighbours	sdpC, sdpR
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

toxins, antitoxins and immunity against toxins, membrane proteins

This gene is a member of the following regulons

AbrB regulon, SdpR regulon

The gene

Basic information

• Locus tag: BSU33780

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): YfhL, YbgB

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity: in the presence of extracellular SdpC, SdpI binds and sequesters SdpR , this results in induction of the sdpR-sdpI operon PubMed

• Interactions:
  • SdpI-SdpR PubMed

• Localization: membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O32241

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: sdpR-sdpI PubMed

• Expression browser: sdpI PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed during logrithmic growth (AbrB) PubMed
  • induced by extracellular SdpC (SdpR) PubMed

• Regulatory mechanism:
  • AbrB: transcription repression PubMed
  • SdpR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

José Eduardo González-Pastor
Cannibalism: a social behavior in sporulating Bacillus subtilis.
FEMS Microbiol Rev: 2011, 35(3);415-24
[PubMed:20955377] [WorldCat.org] [DOI] (I p)