CsbX

• Description: general stress protein
  
  

Gene name	csbX
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: csbX
MW, pI	47 kDa, 8.818
Gene length, protein length	1305 bp, 435 aa
Immediate neighbours	bofC, yrbE
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sporulation proteins, general stress proteins (controlled by SigB), membrane proteins

This gene is a member of the following regulons

CcpA regulon, SigB regulon, SigF regulon, SigG regulon

The gene

Basic information

• Locus tag: BSU27760

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): YoaB

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • forespore intermembrane space (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O05390

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: csbX-bofC PubMed

• Expression browser: csbX PubMed

• Sigma factor: SigF PubMed, SigG PubMed, SigB PubMed

• Regulation:
  • expressed during sporulation in the forespore (SigF, SigG) PubMed
  • induced by stress (SigB) PubMed
  • subject to carbon catabolite repression (CcpA) PubMed

• Regulatory mechanism:
  • CcpA: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Bogumiła C Marciniak, Monika Pabijaniak, Anne de Jong, Robert Dűhring, Gerald Seidel, Wolfgang Hillen, Oscar P Kuipers
High- and low-affinity cre boxes for CcpA binding in Bacillus subtilis revealed by genome-wide analysis.
BMC Genomics: 2012, 13;401
[PubMed:22900538] [WorldCat.org] [DOI] (I e)

A Petersohn, M Brigulla, S Haas, J D Hoheisel, U Völker, M Hecker
Global analysis of the general stress response of Bacillus subtilis.
J Bacteriol: 2001, 183(19);5617-31
[PubMed:11544224] [WorldCat.org] [DOI] (P p)

M Gomez, S M Cutting
Identification of a new sigmaB-controlled gene, csbX, in Bacillus subtilis.
Gene: 1997, 188(1);29-33
[PubMed:9099855] [WorldCat.org] [DOI] (P p)