Difference between revisions of "AzoR2"

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|style="background:#ABCDEF;" align="center"|'''Function''' || resistance to 2-methylhydroquinone
 
|style="background:#ABCDEF;" align="center"|'''Function''' || resistance to 2-methylhydroquinone
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU33540 azoR2]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU33540 azoR2]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 23 kDa, 5.114   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 23 kDa, 5.114   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yvaA]]'', ''[[yvaC]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yvaA]]'', ''[[yvaC]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15359&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU33540 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU33540 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU33540 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:yvaB_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yvaB_context.gif]]

Revision as of 13:51, 13 May 2013

  • Description: similar to NAD(P)H dehydrogenase (quinone)

Gene name azoR2
Synonyms yvaB
Essential no
Product azoreductase
Function resistance to 2-methylhydroquinone
Gene expression levels in SubtiExpress: azoR2
MW, pI 23 kDa, 5.114
Gene length, protein length 633 bp, 211 aa
Immediate neighbours yvaA, yvaC
Sequences Protein DNA Advanced_DNA
Genetic context
YvaB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
AzoR2 expression.png
























Categories containing this gene/protein

sporulation proteins, resistance against oxidative and electrophile stress

This gene is a member of the following regulons

MhqR regulon, SigG regulon

The gene

Basic information

  • Locus tag: BSU33540

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: azoreductase type 1 family (according to Swiss-Prot)
  • Paralogous protein(s): AzoR1

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 3P0R (from B. anthracis, 43% identity, 61% similarity)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • induced by catechol and 2-methylhydroquinone (2-MHQ) (MhqR) PubMed
    • repressed by casamino acids PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References