Difference between revisions of "MleA"
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|style="background:#ABCDEF;" align="center"|'''Function''' || malate utilization | |style="background:#ABCDEF;" align="center"|'''Function''' || malate utilization | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU23550 mleA] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]''' | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yqkK]]'', ''[[mleN]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yqkK]]'', ''[[mleN]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU23550 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU23550 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU23550 Advanced_DNA] |
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|colspan="2" | '''Genetic context''' <br/> [[Image:mleA_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:mleA_context.gif]] | ||
Revision as of 13:13, 13 May 2013
- Description: malic enzyme
| Gene name | mleA |
| Synonyms | yqkJ |
| Essential | no |
| Product | NAD-dependent malate dehydrogenase |
| Function | malate utilization |
| Gene expression levels in SubtiExpress: mleA | |
| Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism | |
| MW, pI | 45 kDa, 4.895 |
| Gene length, protein length | 1317 bp, 439 aa |
| Immediate neighbours | yqkK, mleN |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
utilization of specific carbon sources
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU23550
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: (S)-malate + NAD+ = pyruvate + CO2 + NADH (according to Swiss-Prot) malate --> pyruvate
- Protein family: malic enzymes family (according to Swiss-Prot)
- Paralogous protein(s): YtsJ
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P54572
- KEGG entry: [2]
- E.C. number: 1.1.1.38
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant: GP1136 (cat) available in Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
