Difference between revisions of "Med"
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|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of competence | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of competence | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU11300 med] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/wiki/index.php/Protein_secretion Protein secretion]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/wiki/index.php/Protein_secretion Protein secretion]''' | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yjaV]]'', ''[[comZ]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yjaV]]'', ''[[comZ]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU11300 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU11300 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU11300 Advanced_DNA] |
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|colspan="2" | '''Genetic context''' <br/> [[Image:med_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:med_context.gif]] | ||
Revision as of 12:32, 13 May 2013
- Description: lipoprotein, positive regulator of comK, stimulates KinD-dependent phosphorylation of Spo0A
| Gene name | med |
| Synonyms | yjaW |
| Essential | no |
| Product | positive regulator of comK |
| Function | regulation of competence |
| Gene expression levels in SubtiExpress: med | |
| Metabolic function and regulation of this protein in SubtiPathways: Protein secretion | |
| MW, pI | 35 kDa, 4.599 |
| Gene length, protein length | 951 bp, 317 aa |
| Immediate neighbours | yjaV, comZ |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU11300
Phenotypes of a mutant
- impaired biofilm formation PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family: BMP lipoprotein family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cell surface PubMed
Database entries
- Structure:
- UniProt: O32436
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additonal publications: PubMed
Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647]
[WorldCat.org]
[DOI]
(P p)
Mitsuo Ogura, Hitoshi Hashimoto, Teruo Tanaka
Med, a cell-surface localized protein regulating a competence transcription factor gene, comK, in Bacillus subtilis.
Biosci Biotechnol Biochem: 2002, 66(4);892-6
[PubMed:12036071]
[WorldCat.org]
[DOI]
(P p)
M Ogura, Y Ohshiro, S Hirao, T Tanaka
A new Bacillus subtilis gene, med, encodes a positive regulator of comK.
J Bacteriol: 1997, 179(20);6244-53
[PubMed:9335269]
[WorldCat.org]
[DOI]
(P p)
