GerAC

• Description: lipoprotein, nutrient receptor, germination response to L-alanine
  
  

Gene name	gerAC
Synonyms
Essential	no
Product	nutrient receptor
Function	germination response to L-alanine
Gene expression levels in SubtiExpress: gerAC
Interactions involving this protein in SubtInteract: GerAC
MW, pI	42 kDa, 7.302
Gene length, protein length	1119 bp, 373 aa
Immediate neighbours	gerAB, liaR
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

germination, membrane proteins

This gene is a member of the following regulons

SigF regulon, SigG regulon, SpoVT regulon

The gene

Basic information

• Locus tag: BSU33070

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: gerABKC lipoprotein family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:
  • has an N-terminal signal sequence, lipidated on a Cys residue adjacent to the signal peptide PubMed

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • GerAA-GerAB-GerAC (tentative receptor complex) PubMed
  • GerAC is part of the germinosome in the spore inner membrane PubMed
  • GerAC-Lgt to fix GerAC to diacylglycerol in the membrane PubMed

• Localization: cell membrane (according to Swiss-Prot)
  • outer surface of the inner spore membrane PubMed

Database entries

• Structure:

• UniProt: P07870

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: gerAA-gerAB-gerAC PubMed

• Expression browser: gerAC PubMed

• Sigma factor: SigG PubMed, SigF PubMed

• Regulation:
  • expressed during sporulation in the forespore (SigF, SigG, SpoVT) PubMed
  • expression level depends on sporulation conditions (medim composition, temperature) PubMed

• Regulatory mechanism:
  • SpoVT: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed