Difference between revisions of "RplA"

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=== Additional information===
 
=== Additional information===
 
 
  
  
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* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
 
** [[YsxC]]-[[RplA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/17981968 PubMed]
 
** [[YsxC]]-[[RplA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/17981968 PubMed]
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** [[RplA]]-[[CshA]] {{PubMed|23175651}}
  
 
* '''[[Localization]]:'''
 
* '''[[Localization]]:'''
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=References=
 
=References=
 
'''Additional publications:''' {{PubMed|23002217}}
 
'''Additional publications:''' {{PubMed|23002217}}
<pubmed>17981968,19653700 ,11463749 22848659</pubmed>
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<pubmed>17981968,19653700 ,11463749 22848659 23175651</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 16:50, 26 November 2012

Gene name rplA
Synonyms
Essential no PubMed
Product ribosomal protein L1 (BL1)
Function translation
Gene expression levels in SubtiExpress: rplA
Interactions involving this protein in SubtInteract: RplA
MW, pI 24 kDa, 9.732
Gene length, protein length 696 bp, 232 aa
Immediate neighbours rplK, rplJ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RplA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RplA expression.png















Categories containing this gene/protein

translation, universally conserved proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU01030

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ribosomal protein L1P family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
    • expression transiently increases in the forespore PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Jörg Stülke's lab
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Martin Lehnik-Habrink, Leonie Rempeters, Ákos T Kovács, Christoph Wrede, Claudia Baierlein, Heike Krebber, Oscar P Kuipers, Jörg Stülke
DEAD-Box RNA helicases in Bacillus subtilis have multiple functions and act independently from each other.
J Bacteriol: 2013, 195(3);534-44
[PubMed:23175651] [WorldCat.org] [DOI] (I p)

Alex Rosenberg, Lior Sinai, Yoav Smith, Sigal Ben-Yehuda
Dynamic expression of the translational machinery during Bacillus subtilis life cycle at a single cell level.
PLoS One: 2012, 7(7);e41921
[PubMed:22848659] [WorldCat.org] [DOI] (I p)

Matthew A Lauber, William E Running, James P Reilly
B. subtilis ribosomal proteins: structural homology and post-translational modifications.
J Proteome Res: 2009, 8(9);4193-206
[PubMed:19653700] [WorldCat.org] [DOI] (P p)

Catherine Wicker-Planquart, Anne-Emmanuelle Foucher, Mathilde Louwagie, Robert A Britton, Jean-Michel Jault
Interactions of an essential Bacillus subtilis GTPase, YsxC, with ribosomes.
J Bacteriol: 2008, 190(2);681-90
[PubMed:17981968] [WorldCat.org] [DOI] (I p)

J Mascarenhas, M H Weber, P L Graumann
Specific polar localization of ribosomes in Bacillus subtilis depends on active transcription.
EMBO Rep: 2001, 2(8);685-9
[PubMed:11463749] [WorldCat.org] [DOI] (P p)