Difference between revisions of "ThiL"

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= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
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* '''Operon:''' ''[[thiL]]-[[tsaE]]-[[tsaB]]-[[ydiD]]-[[tsaD]]'' {{PubMed|22383849}}
  
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=thiL_640662_641639_1 thiL] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=thiL_640662_641639_1 thiL] {{PubMed|22383849}}
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<pubmed>19348578 </pubmed>
 
<pubmed>19348578 </pubmed>
 
==Original publications==
 
==Original publications==
<pubmed>16291685,, </pubmed>
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<pubmed>16291685,22383849, </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 11:22, 18 October 2012

  • Description: thiamine-monophosphate kinase

Gene name thiL
Synonyms ydiA, ydxA
Essential no
Product thiamine-monophosphate kinase
Function biosynthesis of thiamine
Gene expression levels in SubtiExpress: thiL
Metabolic function and regulation of this protein in SubtiPathways:
Thiamin
MW, pI 35 kDa, 5.036
Gene length, protein length 975 bp, 325 aa
Immediate neighbours trnE-Asp, ydiB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
ThiL context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ThiL expression.png















Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU05900

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + thiamine phosphate = ADP + thiamine diphosphate (according to Swiss-Prot)
  • Protein family: thiamine-monophosphate kinase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1VQV (from Aquifex aeolicus, 33% similarity, 51% identity)
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications