FlgM

• Description: anti-SigD, regulation of flagellin, motility, and chemotaxis
  
  

Gene name	flgM
Synonyms
Essential	no
Product	anti-SigD
Function	control of SigD activity
Gene expression levels in SubtiExpress: flgM
Interactions involving this protein in SubtInteract: FlgM
MW, pI	9 kDa, 9.918
Gene length, protein length	264 bp, 88 aa
Immediate neighbours	yvyG, yvyF
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sigma factors and their control, motility and chemotaxis

This gene is a member of the following regulons

ComK regulon, DegU regulon, ScoC regulon, SigD regulon

The gene

Basic information

• Locus tag: BSU35430

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: flgM family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: FlgM-SigD PubMed

• Localization:

Database entries

• Structure:

• UniProt: P39809

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:
  • comFA-comFB-comFC-yvyF-flgM-yvyG-flgK-flgL PubMed
  • yvyF-flgM-yvyG-flgK-flgL PubMed
  • flgM-yvyG-flgK-flgL PubMed

• Expression browser: flgM PubMed

• Sigma factor:
  • comFA: SigA PubMed
  • yvyF: SigD PubMed
  • flgM: SigD PubMed

• Regulation:

• Regulatory mechanism:
  • ComK: transcription activation PubMed
  • ScoC: transcription repression PubMed
  • flgM: DegU-P: transcription activation PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • 1A764 (no resistance), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed