IolW

• Description: scyllo-inositol dehydrogenase, general stress protein
  
  

Gene name	yvaA
Synonyms
Essential	no
Product	scyllo-inositol dehydrogenase
Function	unknown
Gene expression levels in SubtiExpress: iolW
MW, pI	39 kDa, 5.457
Gene length, protein length	1074 bp, 358 aa
Immediate neighbours	csoR, azoR2
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of specific carbon sources, general stress proteins (controlled by SigB)

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

• Locus tag: BSU33530

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: gfo/idh/mocA family (according to Swiss-Prot)

• Paralogous protein(s): YfiI, NtdC, YrbE, YteT, YulF, IolG

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 3GFG

• UniProt: O32223

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: iolW PubMed

• Sigma factor: SigB PubMed

• Regulation:
  • induced by stress (SigB) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Tetsuro Morinaga, Hitoshi Ashida, Ken-Ichi Yoshida
Identification of two scyllo-inositol dehydrogenases in Bacillus subtilis.
Microbiology (Reading): 2010, 156(Pt 5);1538-1546
[PubMed:20133360] [WorldCat.org] [DOI] (I p)

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)