Difference between revisions of "ClpE"
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|style="background:#ABCDEF;" align="center"|'''Function''' || protein degradation | |style="background:#ABCDEF;" align="center"|'''Function''' || protein degradation | ||
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+ | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU13700 clpE] | ||
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ClpE ClpE] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ClpE ClpE] |
Revision as of 08:56, 7 August 2012
- Description: ATP-dependent Clp protease-like (class III stress gene)
Gene name | clpE |
Synonyms | ykvH |
Essential | no |
Product | ATP-dependent Clp protease-like |
Function | protein degradation |
Gene expression levels in SubtiExpress: clpE | |
Interactions involving this protein in SubtInteract: ClpE | |
Metabolic function and regulation of this protein in SubtiPathways: Stress | |
MW, pI | 77 kDa, 5.135 |
Gene length, protein length | 2097 bp, 699 aa |
Immediate neighbours | motA, ykvI |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
proteolysis, heat shock proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU13700
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
- A mutation was found in this gene after evolution under relaxed selection for sporulation PubMed
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATPase/chaperone
Extended information on the protein
- Kinetic information:
- Domains: AAA-ATPase PFAM
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O31673
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: clpE PubMed
- Additional information:
Biological materials
- Mutant: clpE::spec available from the Hamoen] Lab
- Expression vector:
- lacZ fusion:
- GFP fusion: C-terminal YFP and CFP fusions (single copy) available from the Hamoen] Lab
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Leendert Hamoen, Newcastle University, UK homepage
Your additional remarks
References
Reviews
Dorte Frees, Kirsi Savijoki, Pekka Varmanen, Hanne Ingmer
Clp ATPases and ClpP proteolytic complexes regulate vital biological processes in low GC, Gram-positive bacteria.
Mol Microbiol: 2007, 63(5);1285-95
[PubMed:17302811]
[WorldCat.org]
[DOI]
(P p)
Original Publications
Additional publications: PubMed