GmuR

Gene name	gmuR
Synonyms	ydhQ
Essential	no
Product	transcriptional repressor (GntR family)
Function	regulation of glucomannan utilization
Gene expression levels in SubtiExpress: gmuR
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	27 kDa, 7.436
Gene length, protein length	711 bp, 237 aa
Immediate neighbours	gmuD, gmuE
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control

This gene is a member of the following regulons

AbrB regulon, CcpA regulon, GmuR regulon

The GmuR regulon:

• gmuB-gmuA-gmuC-gmuD-gmuR-gmuE-gmuF-gmuG

The gene

Basic information

• Locus tag: BSU05850

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O05509

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: gmuB-gmuA-gmuC-gmuD-gmuR-gmuE-gmuF-gmuG PubMed

• Expression browser: gmuR PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by conjac glucomannan (requires GmuG) (GmuR) PubMed
  • induced by cellobiose (GmuR) PubMed
  • subject to carbon catabolite repression (CcpA) PubMed

• Regulatory mechanism:
  • GmuR: transcription repression PubMed
  • CcpA: transcription repression PubMed
  • AbrB: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed